Protein Alignment FoxK and fkh-7

DIOPT Version :10

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_001023147.1
• Gene: fkh-7 / 177340
• WormBaseID: WBGene00001439
• Length: 778
• Species: Caenorhabditis elegans
• Alignment Length: 778
• Identity: 165/778 - (21%)
• Similarity: 265/778 - (34%)
• Gaps: 244/778 - (31%)

  Fly    25 SSSNNNNSIASSHNNNNNIVTVHTVLNNPPTNTAGG-----GVADAATVAIAKDMLQLHHGA--A 82
            ||.:|...:|...::::...:.:..|..|.:|...|     .:....||   :..||:|...  :
 Worm    93 SSDSNLKRLAGPSSSDSAGTSGYGYLPRPASNLPAGINHEFKIDPLQTV---QQFLQMHQSLMNS 154

  Fly    83 AAATAALNNYNNSSNNNNNSADQLTGNSNNSANHPPATSSTTNSSSSSTTSAN-TNNPSANAAST 146
            .:....|:......:.:|:   |.|...||....|..||.:....:.:.:.|| |....||
 Worm   155 PSVPTCLSKLLIDEDQHNH---QSTTTLNNVLAPPMITSESLPRPTQAQSFANSTIGGGAN---- 212

  Fly   147 LTSSSPPYGELRFN--------QEVLPITDAVTVIGRNSSTSLVHFNVAENNLVSRKHFQVLYDV 203
             ||..|...:...|        ||.|......|:....::.||.|...|.|:
 Worm   213 -TSHLPVTLDTGINDNLILLALQERLMRPQQPTLTQSATTPSLSHLAAATNS------------- 263

  Fly   204 ELRAFFVQCLSKNGIFVDDFLQRRNVDPLRLPQRCY---FRFPSTEIRIEFESYVPATSSDAIDG 265
                      |.|...:.      :.|..||.|:.:   ...|.....::..|.:.:.|...
 Worm   264 ----------STNATSLG------SADTTRLIQQMFLGQMLIPQLPAALDLASTIQSASMSL--- 309

  Fly   266 HSPSLVVGGGGGVAGGGAHVIITPLPRD-ELHQQQLHHHQ-------QQP---------HLQQQQ 313
                               .:.|.:|:. ...|..|..|.       .||         |||.:
 Worm   310 -------------------PLQTTIPQPMSAPQHALWQHGMCAWPSCDQPCDSVMALITHLQHE- 354

  Fly   314 HPHHPPA------------------HHLPLQQQQQQQQPAH---HPLPHT---------PHHPLH 348
               |||:                  |.|.:::.:.|....|   .|.|.|         ...||.
 Worm   355 ---HPPSDKSNEEMRNQIEKVESIEHKLSVERSRLQGMMQHLRMKPSPDTTTPNLVKMEAQSPLR 416

  Fly   349 -----------HTALHQQQQRSGSIVVAPPAGAAAHLI-------AGDGPGIYSPLK-------- 387
                       ..|...|||.:....|:|.:.||:.|:       |.....:.||:.
 Worm   417 SPKIEGAAFSIQPAQQFQQQTTSQPQVSPTSEAASSLLSIAATVAASTAAAVTSPINQISTVPSV 481

  Fly   388 -------------ISIPKKEQKS----PYLSPTGTISAANSCPASPRQGFIQN---------QPN 426
                         .|.|..:|.|    |.|....:.::..:.|....:.|:..         ||.
 Worm   482 SSMPSFLNHQLSTSSQPSSQQASGSSGPLLQRAASSASTETSPNPDSKSFVPRRSRISDKTVQPI 546

  Fly   427 NYNNYGNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYR 491
            ..:...|   :|.::|       ::.:|||:||.||.|||..:.|.||||:.||::..:.:.|:|
 Worm   547 ATDIAKN---RDFYRT-------NDVRPPYTYASLIRQAIMESSDCQLTLNEIYTWFTETFAYFR 601

  Fly   492 KETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQGFRP 556
            :.. ..|:|::||||||::.|.:|    ::..||:.|.:| ||      ..|::|..|:|
 Worm   602 RNA-ATWKNAVRHNLSLHKCFQRV----EQNVKGAVWTVD-DS------EFYRRRPNRAS----- 649

  Fly   557 PYGMPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQ 621
               ..||.|.:|...|.|:     |.:...||..|   .||.:..||..:..       .|.|..
 Worm   650 ---ATRSQPQTPLPDDISQ-----QKLFDTSALSS---FLEMQNFDPASLTG-------DQFQLN 696

  Fly   622 QQQQQTLSNNSNQYSSGSPYYVTNQSSGVATPQTHVEGSAASGGGGGGGV-GALLALKRNHVM 683
            ......||..:|              :.|..|...:..:||:|...||.: |.||...:..:|
 Worm   697 GNLDSVLSLLAN--------------ADVNNPLQMLSAAAAAGNHSGGILEGQLLNNVKEEMM 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA_FOXK	151..252	CDD:438740	18/111 (16%)
		FH_FOXK	453..531	CDD:410800	32/77 (42%)
fkh-7	NP_001023147.1	FOXP-CC	326..393	CDD:465036	13/70 (19%)
		FH_FOXP2	562..644	CDD:410839	36/93 (39%)