Protein Alignment FoxK and Foxd2

DIOPT Version :9

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_032619.1
• Gene: Foxd2 / 17301
• MGIID: 1347471
• Length: 492
• Species: Mus musculus
• Alignment Length: 606
• Identity: 141/606 - (23%)
• Similarity: 188/606 - (31%)
• Gaps: 254/606 - (41%)

  Fly   256 PATSSDA---IDGHSPSLVVGGGGGVAGGGAHVIITP-LPRDELHQQQLHHHQQQPHLQQQQHPH 316
            ||..|:.   ||      |||||.|  ||.......| .|||.|                 .|.|
Mouse    17 PAALSEPDADID------VVGGGSG--GGELTARSGPRAPRDVL-----------------PHGH 56

  Fly   317 HPPAHHLPLQQQQQQQQPAHHPLPHTPHHPLHHTALHQQQQRSGSI------VVAPPAGAAAHLI 375
            .||    |.:.:..                     :.:.::.||..      .:||...|||
Mouse    57 EPP----PEEAEAD---------------------VAEDEEESGGCSDCEPRALAPRGAAAA--- 93

  Fly   376 AGD-GPGIYSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNNTQDL 439
            ||. |||:.:....:.|                  ...|..|..|.....|
Mouse    94 AGSPGPGVQAARGATGP------------------GPGPGPPSGGAATRSP-------------- 126

  Fly   440 FQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRH 504
                       ..||||||..||..||..:|.|:||||.|..||...:|||| |....|||||||
Mouse   127 -----------LVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYR-EKFPAWQNSIRH 179

  Fly   505 NLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQGFRPP------------ 557
            |||||..|:|:.|....||||::|.:||:|.....:.|:.:||:|..:...||
Mouse   180 NLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPPPHPHPHPHPELL 244

  Fly   558 ----------------------------------YGMPRSAPVSPSH-----------------M 571
                                              ||.|...|....|                 :
Mouse   245 LRGGAAAAGDPGAFLSSFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPHPHAFAFAATAPCQLSV 309

  Fly   572 DNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQYS 636
            ...|.::|        .||.|..|:...||                    .......:..|....
Mouse   310 PPGRAAAP--------PPGPPTASVFASAA--------------------SAPAPAPAPGSGPSP 346

  Fly   637 SGSP------------YYVTNQSSGVATPQTHVEGSAAS-----------------GGGGGGGVG 672
            :|.|            :|..:.|...|       |:|||                 .||||.|.|
Mouse   347 AGLPAFLGAELGCAKAFYPASLSPPAA-------GTAASLSTALLRQGLKTDAGGGAGGGGAGTG 404

  Fly   673 ALLALKRNHVM---GGGAS-----QHTLHQQQAVA-----QQQHSEIIYEELPTDYSGHIEASEE 724
            ...:...:|:|   ||||:     ..:.....|.|     |.|...::.....|..:|||..|.
Mouse   405 QRPSFSIDHIMGHGGGGAAPPGSGDGSPGSPFAAAAGPGGQAQVLAMLTAPALTPVAGHIRLSH- 468

  Fly   725 ECVTTATDATVAKRPKYVSEV 745
                 ..|:.::..|.:.|:|
Mouse   469 -----PGDSLLSSGPSFASKV 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
		Forkhead	453..540	CDD:278670	47/86 (55%)
Foxd2	NP_032619.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	13..125		39/178 (22%)
		Forkhead	129..215	CDD:278670	47/86 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..344		9/62 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	394..441		14/46 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820