| Sequence 1: | NP_001261701.1 | Gene: | FoxK / 39252 | FlyBaseID: | FBgn0036134 | Length: | 760 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032618.2 | Gene: | Foxc1 / 17300 | MGIID: | 1347466 | Length: | 553 | Species: | Mus musculus |
| Alignment Length: | 466 | Identity: | 126/466 - (27%) |
|---|---|---|---|
| Similarity: | 180/466 - (38%) | Gaps: | 149/466 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 361 SIVVAPPAG-------AAAHLIAGDGPGIYSPLKI-SIPKKEQKSPYLSPTGTISAANSCPASPR 417
Fly 418 QGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSF 482
Fly 483 IVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRR 547
Fly 548 QRSS----------------QGFRPPYGMPRSAPVSPSHMDNSR---ESSP--LQDIVLQS---- 587
Fly 588 ------------------------APGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTL 628
Fly 629 SNNSNQYS--------SGSPY------------------------------YVTNQSSGVATP-- 653
Fly 654 QTHVEGSAASGGGGGGGVGALLALKRNHVMGGGASQHTLHQQ-------------QAVAQQQHSE 705
Fly 706 IIYEELPTDYS 716 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FoxK | NP_001261701.1 | FHA | <170..253 | CDD:238017 | |
| Forkhead | 453..540 | CDD:278670 | 51/86 (59%) | ||
| Foxc1 | NP_032618.2 | Required for transcriptional activation. /evidence=ECO:0000250|UniProtKB:Q12948 | 1..51 | 10/38 (26%) | |
| FH | 78..166 | CDD:214627 | 51/88 (58%) | ||
| Nuclear localization signal 1 (NLS 1). /evidence=ECO:0000250|UniProtKB:Q12948 | 78..93 | 10/14 (71%) | |||
| Nuclear localization signal 2 (NLS 2). /evidence=ECO:0000250|UniProtKB:Q12948 | 168..176 | 3/7 (43%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 173..326 | 23/152 (15%) | |||
| Required for transcriptional inhibition. /evidence=ECO:0000250|UniProtKB:Q12948 | 217..366 | 20/148 (14%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 356..393 | 15/36 (42%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 420..466 | 7/20 (35%) | |||
| Required for transcriptional activation. /evidence=ECO:0000250|UniProtKB:Q12948 | 466..553 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG2294 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1270467at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000010 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.820 | |||||