DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and Foxe3

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_599166.1	Gene:	Foxe3 / 171302	RGDID:	621727	Length:	286	Species:	Rattus norvegicus

Alignment Length:	239	Identity:	77/239 - (32%)
Similarity:	107/239 - (44%)	Gaps:	61/239 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 PAGAAAHLIAGDGPGIYSPLKISIPKKEQKSPYLSPTGTISAANS-CPASPRQGFIQNQPNNYNN 430
            |:|.....:|||.||                  ..|...:...:| .||:|..|..:.:|
  Rat    18 PSGPQPPSLAGDEPG------------------REPEEVVGGGDSEPPAAPGPGRRRRRP----- 59

  Fly   431 YGNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETN 495
                              ....||||||..||..|::.||.::|||:.||.||.:.:.:||....
  Rat    60 ------------------LQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPR 106

  Fly   496 KGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDH-SYKKRRQRSSQGFRP--- 556
            | |||||||||:||..|:||.|....||||::|.:|| :.|.:.|: |:.:||:|..:...|
  Rat   107 K-WQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDP-AAADMFDNGSFLRRRKRFKRTELPAPP 169

  Fly   557 ----PYG----MPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSP 592
                ||.    .|..||..|:.:  .|..|.|.   ||:.|..|
  Rat   170 PPPFPYAPFPPAPAPAPAPPARL--FRLDSLLG---LQTEPPGP 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	44/86 (51%)
Foxe3	NP_599166.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62		14/84 (17%)
Foxe3	NP_599166.1	FH	64..152	CDD:214627	45/89 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820