DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment FoxK and Foxd1

DIOPT Version :9

Sequence 1:NP_001261701.1 Gene:FoxK / 39252 FlyBaseID:FBgn0036134 Length:760 Species:Drosophila melanogaster
Sequence 2:NP_032268.2 Gene:Foxd1 / 15229 MGIID:1347463 Length:456 Species:Mus musculus


Alignment Length:545 Identity:127/545 - (23%)
Similarity:171/545 - (31%) Gaps:249/545 - (45%)


- Green bases have known domain annotations that are detailed below.


  Fly   274 GGGGVAGGGAHVIITPLPRDELHQQQLHHHQQQPHLQQQQHPHHPPAHHLPLQQQQQQ-----QQ 333
            ||||..|||:.     ||...  |::...:..:..|:.             |:::...     .:
Mouse    38 GGGGRGGGGSR-----LPSSA--QRRRRSYAGEDDLED-------------LEEEDDDDLLLASR 82

  Fly   334 PAHHPLPHTPHHPLHHTALHQQQQRSGSIVVAPPAGAAAHLIAGDGPGIYSPLKISIPKKEQKSP 398
            ||..|.|..| .|...|.       ||..     :||.|...||.|.|                 
Mouse    83 PAASPAPPGP-APAPGTG-------SGGC-----SGAGAGGGAGGGTG----------------- 117

  Fly   399 YLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNHNEKPPYSYAQLIV 463
                .||...|.                                      |...||||||..||.
Mouse   118 ----AGTGGGAK--------------------------------------NPLVKPPYSYIALIT 140

  Fly   464 QAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFW 528
            .||..:|.|:||||.|..||...:|||| |....||||||||||||..|:|:.|....||||::|
Mouse   141 MAILQSPKKRLTLSEICEFISSRFPYYR-EKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYW 204

  Fly   529 RIDPDSGAKLIDHSYKKRRQRSSQG------------------------------FRPP------ 557
            .:||:|.....:.|:.:||:|..:.                              |.||      
Mouse   205 TLDPESADMFDNGSFLRRRKRFKRQPLLAPHAAAEALLLRGAGPAAGAGDPGAALFPPPPPPPAC 269

  Fly   558 --------YGM------------------------PRSAPVSP---------------------S 569
                    ||:                        |.|.|..|                     |
Mouse   270 GYGAYGCAYGLQLPPCAPPSALFAAAAAAAAAAFHPHSPPPPPPPPPPPPGAAAELARTAFGYRS 334

  Fly   570 HMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQ 634
            |...:....|||...:::  |.||.:...|                                   
Mouse   335 HALAAALPGPLQAAAVKA--GGPGAAALAR----------------------------------- 362

  Fly   635 YSSGSPYYVTN---QSSGVATPQTHVEGSAASG---GGGGGG------VGALLALKRNHVMGGGA 687
                ||:.:.:   ::.|.|....||...||||   |.||||      .|..:||.|:.|:...|
Mouse   363 ----SPFSIESLIGRTRGPAAAGAHVSSGAASGTAPGPGGGGCAVQAAAGPAVALTRSLVVAAAA 423

  Fly   688 SQH---------TLHQQQAVAQQQH 703
            :..         ||||..|::..::
Mouse   424 AASSVSSSAALGTLHQGTALSSVEN 448

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FoxKNP_001261701.1 FHA <170..253 CDD:238017
Forkhead 453..540 CDD:278670 47/86 (55%)
Foxd1NP_032268.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..104 21/98 (21%)
Forkhead 130..216 CDD:278670 47/86 (55%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 303..322 4/18 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 381..401 10/19 (53%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.910

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