Protein Alignment FoxK and FOXR2

DIOPT Version :10

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_940853.1
• Gene: FOXR2 / 139628
• HGNCID: 30469
• Length: 311
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 58/286 - (20%)
• Similarity: 104/286 - (36%)
• Gaps: 84/286 - (29%)

  Fly   286 IITPLPRDE--LHQQQLHHHQ----QQPHLQQQQHP----HHPPAHH-----------LPLQQQQ 329
            :..|...|:  |.:|.|..::    :.|.:.|::.|    ..||...           .||..|:
Human    30 LFLPCTTDQCSLAEQILAKYRVGVMKPPEMPQKRRPSPDGDGPPCEPNLWMWVDPNILCPLGSQE 94

  Fly   330 QQQQPAHH------PLPHTPHHPLHHTALHQQQQRSGS------IVVAPPAGAAAHLIAGDGP-- 380
            ..:.....      |.|..|            |:..||      :|.:.|:.::.     ..|
Human    95 APKPSGKEDLTNISPFPQPP------------QKDEGSNCSEDKVVESLPSSSSE-----QSPLQ 142

  Fly   381 --GIYSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTP 443
              ||:||....:.::|.:.|  ......|....|..|.:...|.||..::
Human   143 KQGIHSPSDFELTEEEAEEP--DDNSLQSPEMKCYQSQKLWQINNQEKSW--------------- 190

  Fly   444 STASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSL 508
                    ::||.:.:.||..|:...|...|::..||:|..:|:|::....: ||:::|.:||..
Human   191 --------QRPPLNCSHLIALALRNNPHCGLSVQEIYNFTRQHFPFFWTAPD-GWKSTIHYNLCF 246

  Fly   509 NRYFIKVARS-QDEPG---KGSFWRI 530
            ...|.||..| :||..   :...|::
Human   247 LDSFEKVPDSLKDEDNARPRSCLWKL 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA_FOXK	151..252	CDD:438740
		FH_FOXK	453..531	CDD:410800	24/82 (29%)
FOXR2	NP_940853.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..76		5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..171		18/99 (18%)
		FH_FOXR	190..278	CDD:410810	24/107 (22%)