DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and Foxj1

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_446284.2	Gene:	Foxj1 / 116557	RGDID:	621764	Length:	421	Species:	Rattus norvegicus

Alignment Length:	305	Identity:	87/305 - (28%)
Similarity:	126/305 - (41%)	Gaps:	88/305 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   366 PPAGAAAH-------LIAGDGPGIYSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQN 423
            ||.|...|       |:|...|....|..:..|....|     ||.:.::.::.|.      :|.
  Rat    53 PPGGTDPHGYHQVPGLVAPGSPLAADPACLGQPHTPGK-----PTSSCTSRSAPPG------LQA 106

  Fly   424 QPNNYNNYGNNNTQDLFQTPSTASY--NHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKH 486
            .|                 |....|  |.:.|||||||.||..|:.|:...::|||.||.:|..:
  Rat   107 PP-----------------PDDVDYATNPHVKPPYSYATLICMAMQASKATKITLSAIYKWITDN 154

  Fly   487 YPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKR----- 546
            :.|:| ..:..||||||||||||:.||||.|.:||||||.||||||....:|:..::|||
  Rat   155 FCYFR-HADPTWQNSIRHNLSLNKCFIKVPREKDEPGKGGFWRIDPQYAERLLSGAFKKRRLPPV 218

  Fly   547 -------RQRSSQGFRPPYGMPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPE 604
                   ||.:.:....|:|.|.:.        |......||:  .:.|.|..|....:
  Rat   219 HIHPAFARQAAQEPSTAPWGGPLTV--------NREAQQLLQE--FEEATGEGGWGTGE------ 267

  Fly   605 IIYNSQNAHQQQQ------------------QQQQQQQQQTLSNN 631
                .:..|:::|                  .|::|.:.:.|..|
  Rat   268 ----GRLGHKRKQPLPKRVAKVLRPPSTLLLTQEEQGELEPLKGN 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	49/86 (57%)
Foxj1	NP_446284.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..110		8/58 (14%)
		FH_FOXJ1	121..199	CDD:410797	46/78 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	256..277		4/30 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920