DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxe3

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	XP_002931457.1	Gene:	foxe3 / 100495102	XenbaseID:	XB-GENE-480592	Length:	398	Species:	Xenopus tropicalis

Alignment Length:	333	Identity:	97/333 - (29%)
Similarity:	146/333 - (43%)	Gaps:	71/333 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 YSPLKISIPKKEQKSPYLSPTGTI----SAANSCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTP 443
            :||.:.:.|  ...||.:...|::    ....:|  ||.:| :...|:.:|.......:   :.|
Frog    21 HSPTEAASP--IPSSPSMDSPGSVRVKCEPKGTC--SPEEG-VNGLPDEHNQASGGRRR---KRP 77

  Fly   444 STASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSL 508
            .     ...||||||..||..||:.:|:::|||.|||.||::.:|:|| |.:|.|||||||||:|
Frog    78 I-----QRGKPPYSYIALIAMAIANSPERKLTLGGIYKFIMERFPFYR-ENSKKWQNSIRHNLTL 136

  Fly   509 NRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQGFRPPYGMPRSAPVSPSHMDN 573
            |..|:|:.|....||||::|.:||.:.....:.|:.:||:|..:.....|         |.:|.|
Frog   137 NDCFVKIPREPGHPGKGNYWTLDPAAEDMFDNGSFLRRRKRFKRTDLTTY---------PGYMQN 192

  Fly   574 SRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNA----------------HQQQQQQQQQ 622
            |...:|        .|..       ||:.|..||:|..:                |.|......|
Frog   193 SSAFTP--------TPAG-------RASYPTSIYSSVGSGYNPQIHQTHHPAMVHHYQPPGGAGQ 242

  Fly   623 QQQQTLSNNS--NQYSSGSP---YYVTNQSSGVATPQTHVEGSAASG--------GGGGGGVGAL 674
            .|.:..|.:|  ||.|...|   ..:|:.|.|:.....::..|.:.|        .....|||:|
Frog   243 GQHRMFSIDSLINQQSVMQPSPGAELTHHSLGLNGDLGNMTSSCSVGDLSCFQTQSISPTGVGSL 307

  Fly   675 LALKRNHV 682
            |....|.|
Frog   308 LNRPSNAV 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	45/86 (52%)
foxe3	XP_002931457.1	FH	82..170	CDD:214627	45/88 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010