DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxd4l1.2

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	XP_002935635.1	Gene:	foxd4l1.2 / 100485983	XenbaseID:	XB-GENE-876578	Length:	338	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	89/288 - (30%)
Similarity:	116/288 - (40%)	Gaps:	98/288 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 QQQPAHHPLPHTPHHPLHHTA--------------------LHQQQQRSGSIVVAPPAGAAAHLI 375
            |:..||       ||...:|.                    ||..||             ..|..
Frog     5 QKSSAH-------HHAQDYTGVSDEEDEIDILGENDSCNLRLHINQQ-------------PTHSE 49

  Fly   376 AGDGPGIYSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNNTQDLF 440
            .||. |:.||.|:|              ||   .|||.:|..:            .|..:...|.
Frog    50 IGDS-GVLSPSKLS--------------GT---ENSCHSSEEK------------EGGTSKDSLH 84

  Fly   441 QTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHN 505
            .||.:.:.....||||||..||..||..:|.::||||||..||...:||| |:....||||||||
Frog    85 TTPDSKASRAFLKPPYSYIALITMAIVQSPYRKLTLSGICDFISSKFPYY-KDKFPAWQNSIRHN 148

  Fly   506 LSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQ--------GF---RP--- 556
            ||||..|||:.|....||||::|.:||.|.....:.|:.:||:|..:        ||   .|
Frog   149 LSLNDCFIKIPREPGNPGKGNYWTLDPASKDMFDNGSFLRRRKRFKRHHQELIKDGFLMYNPLHY 213

  Fly   557 --PYGMPRS-APV----------SPSHM 571
              ||..|:: .||          .|:|:
Frog   214 ITPYSAPQTQTPVICMAIPQNLAMPNHL 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	47/86 (55%)
foxd4l1.2	XP_002935635.1	Forkhead	97..182	CDD:365978	47/85 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920