DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxg1d

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_001116096.1	Gene:	foxg1d / 100142648	ZFINID:	ZDB-GENE-080305-12	Length:	316	Species:	Danio rerio

Alignment Length:	229	Identity:	82/229 - (35%)
Similarity:	114/229 - (49%)	Gaps:	47/229 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   452 EKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVA 516
            :|||:||..||:.||..:|:|:|||:|||.||:|::|:|| |..:|||||||||||||:.|:||.
Zfish    61 DKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPFYR-EHKQGWQNSIRHNLSLNKCFVKVP 124

  Fly   517 RSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQGFRPPYGMPRSAPVSPSHMDNSRE--SSP 579
            |..|:||||::|.:||.|....|..:..|.|:||:.. |....:.|....||..:....|  ::|
Zfish   125 RHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSATS-RGKLAIKRGLRFSPLGLHGITETANNP 188

  Fly   580 LQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQYSSGSPYYVT 644
            |...:      ||.:||......|.  ||                             |:.:...
Zfish   189 LYWQL------SPLLSLHHHHHHPH--YN-----------------------------GTSHGFL 216

  Fly   645 NQSSGVATPQTHVE--GS----AASGGGGGGGVG 672
            ||:.|..:....||  ||    .|..||..|.:|
Zfish   217 NQAHGYGSFVHGVEHLGSREAPRAVLGGSSGALG 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	50/86 (58%)
foxg1d	NP_001116096.1	FH	62..150	CDD:214627	51/88 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820