DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxe1

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	XP_002936729.1	Gene:	foxe1 / 100038190	XenbaseID:	XB-GENE-478544	Length:	377	Species:	Xenopus tropicalis

Alignment Length:	412	Identity:	104/412 - (25%)
Similarity:	167/412 - (40%)	Gaps:	98/412 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 TALHQQQQRSGSIVVAPPAGAAAHLIAGDGPGIYSPLKISIP-KKEQKSPYLSPTGTISAANSCP 413
            ||.:||     |...|..|||:....:|          :::| .|.:|.|  :|..::|...|
Frog     2 TAENQQ-----SPTRATAAGASLQQASG----------LTMPVVKVEKDP--APEASMSNGGS-- 47

  Fly   414 ASPRQGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSG 478
                :|  ::.|.     |....:.|          ...||||||..||..||:.:.|::|||.|
Frog    48 ----EG--EDTPK-----GRRRKRPL----------QKGKPPYSYIALIAMAIANSTDRKLTLGG 91

  Fly   479 IYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSY 543
            ||.||.:.:|:|| :.:|.|||||||||:||..|||:.|....||||::|.:||::.......|:
Frog    92 IYKFITERFPFYR-DNSKKWQNSIRHNLTLNDCFIKIPREPGRPGKGNYWALDPNAEDMFDSGSF 155

  Fly   544 KKRRQRSSQGFRPPYGMPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYN 608
            .:||:|..:.....|         |:::.::...||||               ..||..|..:|.
Frog   156 LRRRKRFKRTDLTTY---------PAYIHDTSMFSPLQ---------------VARATYPNTVYP 196

  Fly   609 SQNAHQQQQQQQQQQQQQTLSNNSNQYSSGSPYYVT-------------NQSSGVATPQTHVEGS 660
            :........||..........::|..:||..|...:             .|.:...:|:.:...|
Frog   197 NMTMSPSYSQQIAPHSSVYYPSSSPAFSSAQPRVFSINTLIGHSGSEHAQQPNRSISPEVNSTSS 261

  Fly   661 AASGGGGG-----GGVGALLALKRNHVMGGGASQHTLHQQQAVAQQQHSEIIYE----ELPT--- 713
            ::...||.     .|.|.:|....|.......:.| |...|:.....::::...    .:||
Frog   262 SSCNYGGSTYSSQAGSGTMLPRSTNPYSYSVPNSH-LQMNQSSYPHSNAQLFGSASRLPMPTSPP 325

  Fly   714 ------DYSGHIEASEEECVTT 729
                  |:.|.:...:...:||
Frog   326 MNSDAVDFYGRMSPGQYTSLTT 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	45/86 (52%)
foxe1	XP_002936729.1	FH	66..154	CDD:214627	45/88 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010