Protein Alignment CG7638 and TMEM161A

DIOPT Version :9

• Sequence 1: NP_648439.1
• Gene: CG7638 / 39250
• FlyBaseID: FBgn0036133
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_060284.1
• Gene: TMEM161A / 54929
• HGNCID: 26020
• Length: 479
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 177/493 - (35%)
• Similarity: 290/493 - (58%)
• Gaps: 19/493 - (3%)

  Fly     1 MAVLGAQLVITLVMVSVIQKLSPHYSFAKWILCRTGLYRYLHPTDDELRSRGGVPKEKPPKGGRN 65
            |||||.|||:||:..:::.:|:||.|||:|:||...|:||.||:::|||:..|.|:   |:|.:.
Human     1 MAVLGVQLVVTLLTATLMHRLAPHCSFARWLLCNGSLFRYKHPSEEELRALAGKPR---PRGRKE 62

  Fly    66 KQANGSGGAAGAQFHIPRSIEVELLTSPVLERDVVHLRYFTEYQWLLDFSVYTGIVYVVSELFHF 130
            :.|||.  :......:||....:|.|.|:...|.:.||:|.||||.:||:||:|.||:.:|.:::
Human    63 RWANGL--SEEKPLSVPRDAPFQLETCPLTTVDALVLRFFLEYQWFVDFAVYSGGVYLFTEAYYY 125

  Fly   131 YYPLRHEVNLSMVWCLLVIFFALKLLSSLTVLYFQSEESIGERSMVIVACLVYLLVAMVVLIVDE 195
            ......|.|:::.||||.:.|::|:..::|.|||.:||. ||||:.:....::||:||:|.:|.|
Human   126 MLGPAKETNIAVFWCLLTVTFSIKMFLTVTRLYFSAEEG-GERSVCLTFAFLFLLLAMLVQVVRE 189

  Fly   196 RILETGLEDAYASFNASASKFLTEQGLPSSGPASKIVVKFFLAMGCGLLGSLFTFPGLRMAKMHW 260
            ..||.|||...||...:....|.:||...:.|.:|:.::..||:...:||:..||||||:|:.|.
Human   190 ETLELGLEPGLASMTQNLEPLLKKQGWDWALPVAKLAIRVGLAVVGSVLGAFLTFPGLRLAQTHR 254

  Fly   261 DSLKYCRGNRLLQVLLNLSFVLPFILVILWIRPISRDYLTVRVFQGMQQPLLKPHVFETLRLLLV 325
            |:|.......:||.||:.||:.|..::.||.:||:||:|....|...:..||....|::.||.|:
Human   255 DALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPIARDFLHQPPFGETRFSLLSDSAFDSGRLWLL 319

  Fly   326 IFVVVVRFALMPIYLQSYLNLAHDKIMDLRKEAGRITNVEFKQKISSIFYYLCVVTLQFAAPLIL 390
            :.:.::|.|:...:||:||.||..::..||:|||||...|.:|::..::.|:.||:||:..||||
Human   320 VVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREIQQRVVRVYCYVTVVSLQYLTPLIL 384

  Fly   391 CLYLTLMYKSLGGFSWSGIFRESVVLQHECAASETEGAGVAVSQGDGDFNIIESAQSLQASFSSL 455
            .|..||:.|:|||:|| |:....::.....:||       |...|.|:..:.::|..:..:...|
Human   385 TLNCTLLLKTLGGYSW-GLGPAPLLSPDPSSAS-------AAPIGSGEDEVQQTAARIAGALGGL 441

  Fly   456 KNVFSTEVY-KGFLGFATWWSYFTLFATSSLGIVYQSY 492
                .|.:: :|.|.:..||:.......|..|:.:..:
Human   442 ----LTPLFLRGVLAYLIWWTAACQLLASLFGLYFHQH 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7638	NP_648439.1	Tmemb_161AB	2..493	CDD:287270	176/492 (36%)
TMEM161A	NP_060284.1	Tmemb_161AB	2..476	CDD:313494	176/492 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149488
Domainoid	1	1.000	396	1.000	Domainoid score	I753
eggNOG	1	0.900	-	-		E1_KOG3978
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	398	1.000	Inparanoid score	I1954
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59375
OrthoDB	1	1.010	-	-		D385367at33208
OrthoFinder	1	1.000	-	-		FOG0002601
OrthoInspector	1	1.000	-	-		otm40511
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13624
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4356
SonicParanoid	1	1.000	-	-		X1956
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.900