DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Elo68beta and Elovl4

DIOPT Version :9

Sequence 1:	NP_001097580.1	Gene:	Elo68beta / 39245	FlyBaseID:	FBgn0036128	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_683743.2	Gene:	Elovl4 / 83603	MGIID:	1933331	Length:	312	Species:	Mus musculus

Alignment Length:	257	Identity:	118/257 - (45%)
Similarity:	167/257 - (64%)	Gaps:	2/257 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSMGNDTKTESYSYPFADLADERTQDWPLVKSPWNIIALLALYLLMVRYAPKWTARCKPLQLRVP 67
            |:..||| .|.|.:.:. :||:|..||||::|||..|::..||||.|...|||....:|.|:|:.
Mouse    16 STAFNDT-VEFYRWTWT-IADKRVADWPLMQSPWPTISISTLYLLFVWLGPKWMKDREPFQMRLV 78

  Fly    68 LFCHSLAMIFLNGYICLEFLTASLSLGYNFACQECRVSHDPHEIRIAAAMWWFYISKILEFVDTA 132
            |..::..|:.||.:|..|....|.:.||::.||....|:|.:|:|||.|:||:::||.:|::||.
Mouse    79 LIIYNFGMVLLNLFIFRELFMGSYNAGYSYICQSVDYSNDVNEVRIAGALWWYFVSKGVEYLDTV 143

  Fly   133 FFILRHKWNQLSFLHVYHHSTMFLFCWTYVKWLPTGSTFFPSMINSFVHVIMYSYYALSVLGPRV 197
            |||||.|.||:||||||||.|||...|..:||:..|..||.:.:|||:||||||||.|:..||.:
Mouse   144 FFILRKKNNQVSFLHVYHHCTMFTLWWIGIKWVAGGQAFFGAQMNSFIHVIMYSYYGLTAFGPWI 208

  Fly   198 QRFLWWKRYLTGLQLVQFTIIFFWASQLVFRGCEYGKWLTPIGAAYMVPFLFMFGRFYAQKY 259
            |::||||||||.||||||.:.....:..::..|.:.||:.....||.:.|:|:|..||.:.|
Mouse   209 QKYLWWKRYLTMLQLVQFHVTIGHTALSLYTDCPFPKWMHWALIAYAISFIFLFLNFYTRTY 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elo68beta	NP_001097580.1	ELO	48..267	CDD:279492	97/212 (46%)
Elovl4	NP_683743.2	ELO	41..277	CDD:279492	107/230 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..312
		Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03204, ECO:0000269\|PubMed:24569140	308..312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849283
Domainoid	1	1.000	237	1.000	Domainoid score	I2313
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	255	1.000	Inparanoid score	I3157
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	1	1.000	-	-		mtm8727
orthoMCL	1	0.900	-	-		OOG6_100254
Panther	1	1.100	-	-	LDO	PTHR11157
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R389
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.790