DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Elo68beta and ELOVL4

DIOPT Version :9

Sequence 1:	NP_001097580.1	Gene:	Elo68beta / 39245	FlyBaseID:	FBgn0036128	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_073563.1	Gene:	ELOVL4 / 6785	HGNCID:	14415	Length:	314	Species:	Homo sapiens

Alignment Length:	259	Identity:	116/259 - (44%)
Similarity:	171/259 - (66%)	Gaps:	2/259 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTSSMGNDTKTESYSYPFADLADERTQDWPLVKSPWNIIALLALYLLMVRYAPKWTARCKPLQLR 65
            :.|:..||| .|.|.:.:: :||:|.::|||::|||..:::..||||.|...|||....:|.|:|
Human    14 VVSTALNDT-VEFYRWTWS-IADKRVENWPLMQSPWPTLSISTLYLLFVWLGPKWMKDREPFQMR 76

  Fly    66 VPLFCHSLAMIFLNGYICLEFLTASLSLGYNFACQECRVSHDPHEIRIAAAMWWFYISKILEFVD 130
            :.|..::..|:.||.:|..|....|.:.||::.||....|::.||:|||||:||:::||.:|::|
Human    77 LVLIIYNFGMVLLNLFIFRELFMGSYNAGYSYICQSVDYSNNVHEVRIAAALWWYFVSKGVEYLD 141

  Fly   131 TAFFILRHKWNQLSFLHVYHHSTMFLFCWTYVKWLPTGSTFFPSMINSFVHVIMYSYYALSVLGP 195
            |.|||||.|.||:||||||||.|||...|..:||:..|..||.:.:|||:||||||||.|:..||
Human   142 TVFFILRKKNNQVSFLHVYHHCTMFTLWWIGIKWVAGGQAFFGAQLNSFIHVIMYSYYGLTAFGP 206

  Fly   196 RVQRFLWWKRYLTGLQLVQFTIIFFWASQLVFRGCEYGKWLTPIGAAYMVPFLFMFGRFYAQKY 259
            .:|::||||||||.|||:||.:.....:..::..|.:.||:.....||.:.|:|:|..||.:.|
Human   207 WIQKYLWWKRYLTMLQLIQFHVTIGHTALSLYTDCPFPKWMHWALIAYAISFIFLFLNFYIRTY 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elo68beta	NP_001097580.1	ELO	48..267	CDD:279492	97/212 (46%)
ELOVL4	NP_073563.1	ELO	41..278	CDD:279492	106/230 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..314
		Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03204	310..314
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158906
Domainoid	1	1.000	238	1.000	Domainoid score	I2304
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	255	1.000	Inparanoid score	I3179
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	1	1.000	-	-		mtm8493
orthoMCL	1	0.900	-	-		OOG6_100254
Panther	1	1.100	-	-	LDO	PTHR11157
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R389
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.790