| Sequence 1: | NP_001261699.1 | Gene: | APP-BP1 / 39244 | FlyBaseID: | FBgn0261112 | Length: | 524 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003959.3 | Gene: | UBA3 / 9039 | HGNCID: | 12470 | Length: | 463 | Species: | Homo sapiens |
| Alignment Length: | 407 | Identity: | 84/407 - (20%) |
|---|---|---|---|
| Similarity: | 148/407 - (36%) | Gaps: | 69/407 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 30 QTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGNNFFLDSSYLGKSKALAC 94
Fly 95 MQLLQELNPDVN-GDYVDESADFLLANRPNFFDSF-------DLVIASN-LNEQTLLLLAERLWE 150
Fly 151 LN----VPLIYCRSLGMLGTIRLQIRE-----HCIVEAHPDNRQFDLRLEHPFDALREHLDGTEV 206
Fly 207 TSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEM-KADEENYEEAIKAVNTAFG 270
Fly 271 AGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKA---LKHFVIH-------------ENEGHLPLP 319
Fly 320 GVLP---DMTANTDSYIALQHIYRQQALQDADQVYHKCQE------YLKQLALPADSIDERSVRL 375
Fly 376 ICKEAAGLAVIRGTRIA 392 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| APP-BP1 | NP_001261699.1 | APPBP1_RUB | 16..522 | CDD:238770 | 84/407 (21%) |
| ThiF | 17..>171 | CDD:223552 | 40/153 (26%) | ||
| UBA3 | NP_003959.3 | Interaction with UBE2M N-terminus | 53..70 | 3/5 (60%) | |
| Uba3_RUB | 71..368 | CDD:238765 | 65/317 (21%) | ||
| Interaction with UBE2M N-terminus | 157..161 | 1/3 (33%) | |||
| Interaction with UBE2M N-terminus | 192..217 | 7/24 (29%) | |||
| Interaction with NEDD8 | 227..229 | 0/1 (0%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 242..248 | 1/5 (20%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 292..295 | 1/6 (17%) | |||
| Interaction with UBE2M N-terminus | 331..338 | 2/6 (33%) | |||
| Interaction with NEDD8 | 352..357 | 0/4 (0%) | |||
| Interaction with UBE2M core domain | 368..463 | 16/82 (20%) | |||
| E2_bind | 376..461 | CDD:400951 | 14/74 (19%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0476 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||