Protein Alignment APP-BP1 and UBA4

DIOPT Version :9

• Sequence 1: NP_001261699.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_011979.1
• Gene: UBA4 / 856511
• SGDID: S000001153
• Length: 440
• Species: Saccharomyces cerevisiae
• Alignment Length: 435
• Identity: 83/435 - (19%)
• Similarity: 153/435 - (35%)
• Gaps: 110/435 - (25%)

  Fly    13 DKSKKYDRQI---RLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEED 74
            ::.::|.||:   ...|..||..|:...|.:|....:||.....|...|:|...:.|...|:..:
Yeast    42 EEYQRYGRQMIVEETGGVAGQVKLKNTKVLVVGAGGLGCPALPYLAGAGVGQIGIVDNDVVETSN 106

  Fly    75 LGNNFFLDSSYLGKSKALACMQLLQELNPDVNGDYVDESADFLLANRPNFFDSFDLVIASNLNEQ 139
            |......|||.:|..|..:..|.:.:|||.:|  .|........:|..:.|..::.::....:..
Yeast   107 LHRQVLHDSSRVGMLKCESARQYITKLNPHIN--VVTYPVRLNSSNAFDIFKGYNYILDCTDSPL 169

  Fly   140 TLLLLAERLWELNVPLIYCRSLGMLGTIRLQIREH------CIVEAHPDNRQFDLRLEHPFDALR 198
            |..|:::....|.:.::....||..|.:.:....:      |.....|           |.:|:.
Yeast   170 TRYLVSDVAVNLGITVVSASGLGTEGQLTILNFNNIGPCYRCFYPTPP-----------PPNAVT 223

  Fly   199 EHLDGTEV--------------TSKV-----------PWLLVLHKYLNVWQKQQADGTQTPRNYK 238
            ...:|..:              |.|:           |:|::...:     .||:..|...|..:
Yeast   224 SCQEGGVIGPCIGLVGTMMAVETLKLILGIYTNENFSPFLMLYSGF-----PQQSLRTFKMRGRQ 283

  Fly   239 EK----NQLKETIREEMKADEENYEEAIKAVN------------TAFGAGQVPKSLKAIFEDDAC 287
            ||    .:.:...:|.::..|.|||....|.|            .||         :.|::||
Yeast   284 EKCLCCGKNRTITKEAIEKGEINYELFCGARNYNVCEPDERISVDAF---------QRIYKDD-- 337

  Fly   288 EQLNKKSNVFWIMAKALKHFVIHENEGHLPLPGVLPDMTANTDSYIALQHIYRQQALQDADQVYH 352
            |.|.|  ::| :..:...|:.|    .|.|....:|                 .:.|:|.:....
Yeast   338 EFLAK--HIF-LDVRPSHHYEI----SHFPEAVNIP-----------------IKNLRDMNGDLK 378

  Fly   353 KCQEYLKQLALPADSI-------DERSVRLICKEAAGLAVIRGTR 390
            |.||.|..:...::.:       |.:....:.|:..|.:.:|..|
Yeast   379 KLQEKLPSVEKDSNIVILCRYGNDSQLATRLLKDKFGFSNVRDVR 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_001261699.1	APPBP1_RUB	16..522	CDD:238770	83/432 (19%)
		ThiF	17..>171	CDD:223552	36/156 (23%)
UBA4	NP_011979.1	ThiF_MoeB_HesA_family	46..279	CDD:238386	48/250 (19%)
		RHOD_ThiF	316..440	CDD:238784	25/143 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810