Protein Alignment APP-BP1 and ULA1

DIOPT Version :10

• Sequence 1: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_015322.1
• Gene: ULA1 / 856104
• SGDID: S000005924
• Length: 462
• Species: Saccharomyces cerevisiae
• Alignment Length: 552
• Identity: 138/552 - (25%)
• Similarity: 230/552 - (41%)
• Gaps: 134/552 - (24%)

  Fly    16 KKYDRQIRLWGEHGQTLLEAATVCLVN-VTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGNNF 79
            ::||||:||||..||..|..:.||:|. .|.:..|..|.|||.||...|
Yeast     2 ERYDRQLRLWGALGQDSLNRSRVCVVGPATPLLQEVFKNLVLAGISSLT---------------- 50

  Fly    80 FLDSSYLGKSKALACMQLLQELNPDVNGDYVDESADF-LLANRPNF-FDSFDLVIASNLNEQTLL 142
            :|......:|.:|...:|.::|.|..:.....|..|. ....:|.: :..|.:||.:.:.|||.:
Yeast    51 WLKVECAVQSGSLFLAELKKDLEPLASKQLEYEENDLRKTLQQPQYDWTRFSVVILTCIGEQTAM 115

  Fly   143 LLAERLWELN----------VPLIYCRSLGMLGTIRLQIRE-HCIVEAHPDNRQFDLRLEHPFDA 196
            |      :||          .|::.....|..|.|.|.:.| |.:::||||::::||||::|:..
Yeast   116 L------DLNEIRRQRGTKFPPVLNTFVSGFYGYIYLVLSETHFVLQAHPDSKKYDLRLQNPWPE 174

  Fly   197 LREHLD-------GTEVTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEMKAD 254
            |..::|       .|...|.:|:.::|.|.:   .|.:.||........:..::.:.|...:..|
Yeast   175 LINYVDTFDLSKMDTATFSGIPYTVLLMKCI---AKLERDGNNGRITIDQMKKVLDQICLPLGND 236

  Fly   255 ---EENYEEAIKAVNTAFGAGQVPKSLKAIFEDDACEQL-----NKKSNVF---W-------IMA 301
               |.||.||.:            .:..|..::|.|::|     |.:.:.:   |       |:.
Yeast   237 VIYEPNYVEAKR------------YAYLACSQNDCCKELEDLLRNLEISDYGNDWHDTYNYEILT 289

  Fly   302 KALKHFVIHENEGHL---PLPGVLPDMTANTDSYIALQHIYRQQALQDADQVYHKCQEYLKQLAL 363
            ..|....|.:..|.|   ||.|.||||.:.|::||.|:.:|..:|..|..:|    :|.|
Yeast   290 LLLTLKNIAKENGELSFQPLTGTLPDMESTTENYIRLKKLYEVKAKLDKSRV----EESL----- 345

  Fly   364 PADSIDERSVRLICKEAAGLAVIRGTRIAEEYEKSSRLLPLVEDNELQGNLTAYNFALRAYERFL 428
                  .||.:::.::..       ......|.:..::||  ..::|.|..:..|..|
Yeast   346 ------ARSKKIVSQDVL-------ETFCSHYGEVRKILP--PKSDLLGIFSTSNALL------- 388

  Fly   429 SECGNIPGECIVEQDIGRLKSIAAKMLSD-LGMHATISDDVLHEICRYGGAELHAVSAFIGGCAA 492
                    :.:|........::.|:...: :|:.  :.|:             ::|.||.||...
Yeast   389 --------DALVMVQFWEQPAVTAEDKDEFIGLR--VDDN-------------YSVMAFFGGAVV 430

  Fly   493 QEVIKIITKQYKPIDNTFIYNAITTESVTLKL 524
            ||.||:||..|.||||.|:||.|...|.|.|:
Yeast   431 QEAIKLITHHYVPIDNLFLYNGINNSSATYKI 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	136/548 (25%)
ULA1	NP_015322.1	E1_enzyme_family	2..460	CDD:451392	136/548 (25%)