Protein Alignment APP-BP1 and SAE2

DIOPT Version :10

• Sequence 1: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_973506.1
• Gene: SAE2 / 816686
• AraportID: AT2G21470
• Length: 700
• Species: Arabidopsis thaliana
• Alignment Length: 560
• Identity: 115/560 - (20%)
• Similarity: 198/560 - (35%)
• Gaps: 193/560 - (34%)

  Fly    30 QTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGNNFFLDSSYLGKSKALAC 94
            |:.::.|.|.:|....:|||..|.|.|.|.....:.|..|::..:|...|....|::|:|||...
plant     7 QSAIKGAKVLMVGAGGIGCELLKTLALSGFEDIHIIDMDTIEVSNLNRQFLFRRSHVGQSKAKVA 71

  Fly    95 MQLLQELNPDVN-GDYVDESADFLLANRPN------FFDSFDLVI--ASNLNEQ----TLLLLAE 146
            ...:....|::| ..|        .||..|      ||..||:|:  ..||:.:    .|.|.|:
plant    72 RDAVLRFRPNINIRSY--------HANVKNPEFDVDFFKQFDVVLNGLDNLDARRHVNRLCLAAD 128

  Fly   147 RLWELNVPLIYCRSLGMLGTIRLQIR-----------------------------EHCIV----- 177
                  |||:...:.|.||.:.:.|:                             .||||
plant   129 ------VPLVESGTTGFLGQVTVHIKGKTECYECQTKPAPKTYPVCTITSTPTKFVHCIVWAKDL 187

  Fly   178 -------EAHPDN---------------------RQFDLRLEHPFDALREHLDGTEVTSKVPWLL 214
                   :.:.||                     |..|..:|.....:.:|:.|:.:.:.:
plant   188 LFAKLFGDKNQDNDLNVRSNNSASSSKETEDVFERSEDEDIEQYGRKIYDHVFGSNIEAAL---- 248

  Fly   215 VLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREE-----------------------MKADEE 256
               .....|:.:     :.||....|:.|.|::.::                       :|..:|
plant   249 ---SNEETWKNR-----RRPRPIYSKDVLPESLTQQNGSTQNCSVTDGDLMVSAMPSLGLKNPQE 305

  Fly   257 ------NYEEAIKAVNTAFGAGQVPKSLKAI----FEDD---ACEQLNKKSNV----FWIMAKAL 304
                  |....|:|:...|.     |..|.|    |:.|   |.|.:...:|:    |.|...:|
plant   306 LWGLTQNSLVFIEALKLFFA-----KRKKEIGHLTFDKDDQLAVEFVTAAANIRAESFGIPLHSL 365

  Fly   305 KHFVIHENEGHLPLPGVLPDMTANTDSYIA-LQHIYRQQAL-QDADQ---VYHKCQEY--LKQLA 362
                 .|.:|   :.|.:....|.|::.|| |..|...:.| :|.|:   .|  |.|:  .|.|.
plant   366 -----FEAKG---IAGNIVHAVATTNAIIAGLIVIEAIKVLKKDVDKFRMTY--CLEHPSKKLLL 420

  Fly   363 LPADSIDERSVRLICKEAAGLAVI--RGTRIAEEYEK--SSRL---LPLVEDNELQGN------- 413
            :|.:..:......:|.|...:..|  |.:::.:..:|  .::|   |||:    :.||
plant   421 MPIEPYEPNPACYVCSETPLVLEINTRKSKLRDLVDKIVKTKLGMNLPLI----MHGNSLLYEVG 481

  Fly   414 -------LTAYNFALRAYERFLSECGN--IPGECIVEQDI 444
                   :..||..|   |::|||..:  :.|..:..:|:
plant   482 DDLDDIMVANYNANL---EKYLSELPSPILNGSILTVEDL 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	115/560 (21%)
SAE2	NP_973506.1	Uba2_SUMO	14..435	CDD:238766	93/461 (20%)
		UAE_UbL	442..531	CDD:464286	18/84 (21%)