Protein Alignment APP-BP1 and Uba2

DIOPT Version :10

• Sequence 1: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 126/545 - (23%)
• Similarity: 201/545 - (36%)
• Gaps: 153/545 - (28%)

  Fly    30 QTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGNNFFLDSSYLGKSKALAC 94
            |.|::.:.|.:|....:|||..|.|||.|.....:.|..|:...:|...|.....::|||||...
  Fly    14 QELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVA 78

  Fly    95 MQLLQELNPDVN-GDYVDE--SADFLLANRPNFFDSFDLVIASNLNEQTLLLLAERLWELNVPLI 156
            .:.....|||.. ..|.|.  |.|:.:    |||..||||:::..|......:.......:||||
  Fly    79 RESALSFNPDAKITAYHDSVTSTDYGV----NFFKKFDLVLSALDNRAARNHVNRMCLNADVPLI 139

  Fly   157 YCRSLGMLGTIRL-----------------------QIRE------HCIVEA-HPDNRQFDLRLE 191
            ...:.|..|.:.|                       .||.      ||||.| |..|:.|...||
  Fly   140 ESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAKHLFNQLFGESLE 204

  Fly   192 HPFDALREHL--DGTEVTSKVPWLLVLHKYLNVWQKQQADGTQTPR-NYKEKNQLKETIREEMKA 253
            .      |.:  |..:..:|              :|...||...|: :.|||.   |..:||.:|
  Fly   205 D------EDISPDAADPDAK--------------EKDGGDGNGEPKGDGKEKG---EESKEEKEA 246

  Fly   254 DEENYEEAIKAVNTA-------FGAGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKALKHFVIHE 311
            .|:.....|..:||.       :.||   |.....|.:| ...|.:.||: |...||
  Fly   247 KEDTANGNIMRINTRQWAKDCNYDAG---KLFNKFFNED-ITYLLRMSNL-WKTRKA-------- 298

  Fly   312 NEGHLPLP----GVLPDMTANTDSYIALQHIYRQQALQDADQVYHKCQEYLKQLA---------- 362
                 |:|    .:||:.::.....:|.|| ::..::::..||:   ...||:|:
  Fly   299 -----PVPVQWDTLLPEGSSGDQKDVAKQH-HKVWSIEECAQVF---ANSLKELSANFLKLEGDD 354

  Fly   363 -LPADSIDERSVRLICKEAAGLAVIRGTRIAEEYEKSSRLLPLVEDNELQGN----------LTA 416
             |..|..|:.::..:    |..|.:|....  :.|:.||.    |...:.||          :||
  Fly   355 TLAWDKDDQPAMDFV----AACANVRSHIF--DIERKSRF----EIKSMAGNIIPAIATTNAITA 409

  Fly   417 YNFALRAYERFLSECGNIPGECIVEQDIGRLKSIAAKMLSDLGMHATISDDVLHEICRYGGAELH 481
            ....:||::             ::|....:.|::.|::..:...|..:.|           |.|.
  Fly   410 GISVMRAFK-------------VLEAKWEQCKAVYARLRPNARNHFLVPD-----------ASLP 450

  Fly   482 AVSAFIGGCAAQEVI--KIITKQYK 504
            ..:.....||:...|  ||.||:.:
  Fly   451 GPNPNCHVCASDPAITLKIDTKRMR 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	126/545 (23%)
Uba2	NP_524756.2	Uba2_SUMO	21..459	CDD:238766	117/520 (23%)
		UAE_UbL	467..552	CDD:464286	4/9 (44%)