Protein Alignment APP-BP1 and sae1

DIOPT Version :10

• Sequence 1: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001002058.1
• Gene: sae1 / 415148
• ZFINID: ZDB-GENE-040625-21
• Length: 348
• Species: Danio rerio
• Alignment Length: 515
• Identity: 100/515 - (19%)
• Similarity: 165/515 - (32%)
• Gaps: 195/515 - (37%)

  Fly    13 DKSKKYDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGN 77
            :::.:|||||||||...|..|..:.|.||.:..:|.|.||.|:|.|:.|.|:.|...|.||....
Zfish    15 EEAAQYDRQIRLWGLDAQKRLRGSRVLLVGLRGLGAEVAKNLILAGVKGLTLLDHEQVTEESRRA 79

  Fly    78 NFFLDSSYLGKSKALACMQLLQELNP--DVNGDY--VDESADFLLANRPNFFDSFDLVIASNLNE 138
            .|.:.....|::.|.|.::..|.|||  :|..|.  |:...|       :||..||.|..:..:.
Zfish    80 QFLIPVDADGQNHAQASLERAQFLNPMVEVKADTEPVESKPD-------DFFFQFDAVCLTRCSR 137

  Fly   139 QTLLLLAERLWELNVPLIYCRSL-GMLGTIRLQI-REHCIVEAHPDNRQFDLRLEHPFDALREHL 201
            ..::.:.:.....|:. ::|..: |..|.:...: :|:..||..|
Zfish   138 DLMVRVDQLCASRNIK-VFCGDVYGYNGYMFSDLGQEYHYVEEKP-------------------- 181

  Fly   202 DGTEVTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEMKADEENYEEAIKAVN 266
                                                                      :.:|..|
Zfish   182 ----------------------------------------------------------KVVKGSN 188

  Fly   267 TAFGAGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKALKHFVIHENEGHLPLPGVLPDMTANTDS 331
            .|               :|..|....|               |..||         ..|...|.|
Zfish   189 EA---------------NDGPEAKKPK---------------IDPNE---------TTMVKKTIS 214

  Fly   332 YIALQHIYRQQALQDADQVYHKCQEYLKQLALPADSIDERSVRLICKEAAGLAVIRGTRIAEEYE 396
            :.:|     ::|| :.|....|.:..||:  :|||
Zfish   215 FCSL-----KEAL-EVDWTTEKAKSSLKR--IPAD------------------------------ 241

  Fly   397 KSSRLLPLVEDNELQGNLTAYNFALRAYERFLSECGNIPGECIVEQDIGRLKSIAAKMLSDLGMH 461
                                 .|.|:...:|.::.|..|......:|...|..|...:|..:|
Zfish   242 ---------------------YFLLQVLLKFRTDKGRDPQPDSFAEDSQLLLQIRDDVLETMG-- 283

  Fly   462 ATISDDVL-HEICRYGGAELHAVSAFIGGCAAQEVIKIITKQYKPIDNTFIYNAITTESV 520
              :|.|:| :....|..:|:..|.|.:||...||::|.::::..|..|.|.::.:....|
Zfish   284 --LSSDLLPNTFVSYCFSEMSPVCAVVGGVLGQEIVKALSQRDAPHRNFFFFDGLKGSGV 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	100/512 (20%)
sae1	NP_001002058.1	Aos1_SUMO	17..343	CDD:238769	100/513 (19%)
		E1_4HB	211..274	CDD:465055	19/121 (16%)