Protein Alignment APP-BP1 and uba1

DIOPT Version :10

• Sequence 1: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_998227.1
• Gene: uba1 / 406335
• ZFINID: ZDB-GENE-040426-2009
• Length: 1058
• Species: Danio rerio
• Alignment Length: 528
• Identity: 96/528 - (18%)
• Similarity: 166/528 - (31%)
• Gaps: 183/528 - (34%)

  Fly    18 YDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGNNFFLD 82
            |.||:.:.|......::::.|.:..:..:|.|.||.::|.|:...|:.|....:.:||.:.|:|.
Zfish    55 YSRQLYVLGHDAMKRMQSSNVLISGLRGLGVEIAKNVILGGVKSVTLHDQGVAEWKDLSSQFYLR 119

  Fly    83 SSYLGKSKALACMQLLQELNPDVNGDYVD-ESADFLLANRPNFFDSFDLVIASN--LNEQTLLLL 144
            ...|||::|......|.|||     .||. .|....|.|  .:...|.:|:.:|  |:|||
Zfish   120 EEDLGKNRADVSQPRLAELN-----SYVPVTSYTGTLTN--EYLTKFQVVVLTNSSLDEQT---- 173

  Fly   145 AERLWEL----NVPLIYCRSLGMLGTIRLQIREHCIVEAHPDNRQFDLRLEHPFDALREHLDGTE 205
              |:.|.    .:.||...:.|:.|.:.....|..||        ||...|.|..|:
Zfish   174 --RIGEFCHSNGIKLIVADTRGLFGQLFCDFGEVMIV--------FDTNGEQPLSAM-------- 220

  Fly   206 VTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEMKADEENYEEAIKAVNTAFG 270
                                                                             
Zfish   221 ----------------------------------------------------------------- 220

  Fly   271 AGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKALKHFVIHENEGHLPLPGVLPDMTANTDSYIAL 335
                   :..|.:|.|        .|...:.:|...|                    .:..|:..
Zfish   221 -------ISMITKDSA--------GVVTCLDEARHGF--------------------ESGDYVTF 250

  Fly   336 QHIYRQQALQDADQVYHKCQEYLKQLALPADSIDERSVRLICKEAAGLAVIRGTRIAEEYEKSSR 400
            ..:.....|...|.|      .:|.|.....|        ||..::....:||..:.:     .:
Zfish   251 TEVQGMTELNGCDPV------EIKTLGPYTFS--------ICDTSSFSDYVRGGIVTQ-----VK 296

  Fly   401 LLPLVEDNELQGNLTAYNFALRAYERFLSECGNIPGECIV--------------------EQDIG 445
            :...:....|..::....|.|..:.:|     :.||:..|                    :.|..
Zfish   297 MPKKIAFKSLSSSMAEPEFLLTDFAKF-----DRPGQLHVGFQALHAFEKKHSRLPKPWNQADAD 356

  Fly   446 RLKSIAAKM---LSDLGMHATISDDVLHEICRYGGAELHAVSAFIGGCAAQEVIKIITKQYKPID 507
            .|.::|.::   .:.......:...|:.::......:|..|:|||||.|||||:|..|.::.||.
Zfish   357 ELMTLAEEVNAAQTGSAKQEELDQAVIKKLACVAAGDLAPVNAFIGGLAAQEVMKACTGKFMPIM 421

  Fly   508 NTFIYNAI 515
            ....::|:
Zfish   422 QWLYFDAL 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	96/528 (18%)
uba1	NP_998227.1	Ube1	49..1055	CDD:273603	96/528 (18%)