Protein Alignment APP-BP1 and Uba1

DIOPT Version :10

• Sequence 1: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_477310.2
• Gene: Uba1 / 35998
• FlyBaseID: FBgn0023143
• Length: 1191
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 99/545 - (18%)
• Similarity: 197/545 - (36%)
• Gaps: 140/545 - (25%)

  Fly    17 KYDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGI----GGFTVADGSTVKEEDLGN 77
            :||.||.::|:..|..|..:...:|...|:|||..|...:.|:    |...|.|...:::.:|..
  Fly   586 RYDSQIAIFGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEKSNLNR 650

  Fly    78 NFFLDSSYLGKSKALACMQLLQELNPDVNGDYVD--ESADFLLANRPNFFDSFDLVIASNLNEQT 140
            .|......:.|.|::.....::.:||:||....:  ..|:.......:||...| .:|:.|:...
  Fly   651 QFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLD-GVANALDNVD 714

  Fly   141 LLLLAERLWELN-VPLIYCRSLGMLGTIRLQI----REHCIVEAHPDN-------RQFDLRLEHP 193
            ..:..:|....| :||:...:||.||.:::.:    ..:...:..|:.       :.|...:||.
  Fly   715 ARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHT 779

  Fly   194 FDALREHLDG------------------TEVTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEK 240
            ....|:..:|                  ||..:|:|.:..|
  Fly   780 LQWARDAFEGVFKQSAENAAQYIADPQFTERIAKLPGIQPL------------------------ 820

  Fly   241 NQLKETIREEMKADE-ENYEEAIKAVNTAFGAGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKAL 304
             ::.::|::.:..|: :::...::... .:...|....:|.:..:...:|:......||
  Fly   821 -EILDSIKKALIDDKPKSFAHCVEWAR-LYWEDQYVNQIKQLLFNFPPDQITSSGQPFW------ 877

  Fly   305 KHFVIHENEGHLPLPGVLPD-MTANTDSYIALQHIYRQQALQ----DADQVYHK--CQEYLKQLA 362
                    .|    |...|| :..:.:..:.|..||....|:    ..:||.::  ..|.::::.
  Fly   878 --------SG----PKRCPDPLVFDVNDPMHLDFIYAAANLRAEVYGIEQVRNRETIAELVQKVK 930

  Fly   363 LPADSIDERS-VRLICKEAAGLAVIRG---------------TRIAEEYEKSSRLLPLVEDNELQ 411
            :|  ....|| |::...|||..|....               :.:.:..:|||::.||..:.:..
  Fly   931 VP--EFKPRSGVKIETNEAAAAASANNFDDGELDQDRVDKIISELLKNADKSSKITPLEFEKDDD 993

  Fly   412 GNLTAYNFALRAYERFLSECGNI--PGECIVEQDIGRLKSIAAKMLSDLGMHATISDDVLHEICR 474
            .||         :..|:..|.|:  ....|...|..:.|.||.|::..:.
  Fly   994 SNL---------HMDFIVACSNLRAANYKIPPADRHKSKLIAGKIIPAIA--------------- 1034

  Fly   475 YGGAELHAVSAFIGGCAAQEVIKII 499
                   ..::.:.|.|..||||:|
  Fly  1035 -------TTTSVLSGLAVLEVIKLI 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	99/545 (18%)
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	99/545 (18%)