Protein Alignment APP-BP1 and Uba1

DIOPT Version :10

• Sequence 1: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_552371.4
• Gene: Uba1 / 3291445
• VectorBaseID: AGAMI1_003109
• Length: 1105
• Species: Anopheles gambiae
• Alignment Length: 561
• Identity: 100/561 - (17%)
• Similarity: 188/561 - (33%)
• Gaps: 152/561 - (27%)

  Fly    10 ELSDKSKKYDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGI-----GGFTVADGST 69
            |.:....:||.||.::|...|.:|......:|...|:|||..|...:.|:     |...|.|...
Mosquito   485 ECAPTGSRYDGQIAVFGRKFQDVLGQLKYFIVGAGAIGCELLKNFAMIGVASKGDGEIIVTDMDL 549

  Fly    70 VKEEDLGNNFFLDSSYLGKSKALACMQLLQELNPDVN--------GDYVDESADFLLANRPNFFD 126
            :::.:|...|......:.:.|:....|.::.:|.|:.        |...:...|      ..||:
Mosquito   550 IEKSNLNRQFLFRPHDVQQPKSRVAAQAVKRMNGDIKVTSHENRVGPETERFYD------DTFFN 608

  Fly   127 SFDLVIASNLNEQTLLLLAERLWELNVPLIYCRSLGMLGTIRLQI----REHCIVEAHPDN---- 183
            ..|.|..:..|....:.:..|......||:...:||.||.|::.:    ..:...:..|:.
Mosquito   609 RLDGVANALDNIDARIYMDRRCVYYRKPLLESGTLGTLGNIQVVVPFLTESYSSSQDPPEKSIPI 673

  Fly   184 ---RQFDLRLEHPFDALREHLDG--TEVTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYK----E 239
               :.|...:||.....|:..:|  .:|.....      :|:       :|.|...|..|    :
Mosquito   674 CTLKNFPNAIEHTLQWARDTFEGIFKQVAENAA------QYI-------SDPTFIERTLKLPGVQ 725

  Fly   240 KNQLKETIREEMKADE-ENYEEAIKAVNTAFGAGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKA 303
            ..:..|::::.:..|. ::.|:.:|.....| ..|....::.:..:...:|::.....||...|.
Mosquito   726 PLEALESVKKALIDDRPKSIEDCVKWARMYF-EEQYSNQIRQLLFNFPPDQMSSTGQPFWSGPKR 789

  Fly   304 LKHFVIHENEGHLPLPGVLPDMTANTDSYIALQHIY--RQQALQDADQVYHKCQEYLKQLALP-- 364
            |...:..:.|..|.|..:.  .|||..:     .:|  .||..:||      .::.:..:.:|
Mosquito   790 LPEAITFDPEEPLHLDYIF--ATANLKA-----EVYGIPQQRNRDA------IRKIVMTIEVPKF 841

  Fly   365 ------------------------------ADSIDERSVRLICKEAAGLAVIRGTRIAEEYEKSS 399
                                          .:.:|...:..:..|.|.|.....|....|:||.
Mosquito   842 TPRSGVKIAVTDSALQAEENGGGGGGGGAGGEDLDPDRIGRLQSELAALGKPDFTITPLEFEKD- 905

  Fly   400 RLLPLVEDNELQ-------GNLTAYNFALRAYERFLSECGNIPGECIVEQDIGRLKSIAAKMLSD 457
                  :||.|.       .||.|.|:.:...:|..|                  |.||.|::..
Mosquito   906 ------DDNNLHMDFIVAASNLRAANYKIPPADRHKS------------------KLIAGKIMPA 946

  Fly   458 LGMHATISDDVLHEICRYGGAELHAVSAFIGGCAAQEVIKI 498
            :.                      ..::.:.|||:.|:.|:
Mosquito   947 IA----------------------TTTSLVAGCASLELYKL 965

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	99/555 (18%)
Uba1	XP_552371.4	None