Protein Alignment APP-BP1 and Uba1

DIOPT Version :10

• Sequence 1: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001014102.1
• Gene: Uba1 / 314432
• RGDID: 1359327
• Length: 1058
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 102/523 - (19%)
• Similarity: 171/523 - (32%)
• Gaps: 173/523 - (33%)

  Fly    18 YDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGNNFFLD 82
            |.||:.:.|.....:|:.::|.:..:..:|.|.||.::|.|:...|:.|..|.:..||.:.|:|.
  Rat    55 YSRQLYVLGHEAMKMLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADLSSQFYLR 119

  Fly    83 SSYLGKSKALACMQLLQELNPDV-----NGDYVDESADFLLANRPNFFDSFDLVIASN--LNEQT 140
            ...:||::|......|.|||..|     .|..|::           |...|.:|:.:|  |.||
  Rat   120 EEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVED-----------FLSGFQVVVLTNSPLEEQ- 172

  Fly   141 LLLLAERLWELNVPLIYCRSLGMLGTIRLQIREHCIVEAHPDNRQFDLRLEHPFDA--------- 196
             |.:.|......:.|:...:.|:.|.:.....|..::.        |...|.|..|
  Rat   173 -LRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMVLT--------DSNGEQPLSAMVSMVTKDN 228

  Fly   197 ------LREHLDGTEVTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEMKADE 255
                  |.|...|.|....|       .:..|....|.:|.| |...|.......:|     .|.
  Rat   229 PGVVTCLDEARHGFETGDFV-------SFSEVQGMVQLNGCQ-PIEIKVLGPYTFSI-----CDT 280

  Fly   256 ENYEEAIKA--VNTAFGAGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKALKHFVIHENEGHLPL 318
            .|:.:.|:.  |:..    :|||            :::.||                     ||.
  Rat   281 SNFSDYIRGGIVSQV----KVPK------------KISFKS---------------------LPA 308

  Fly   319 PGVLPDMTANTDSYIALQHIYRQQALQDADQVYHK-CQEYLKQLALPADSIDERSVRLICKEAAG 382
            ....||... ||    .....|...|....|..|: |.::.:.   |....:|.:..|:.
  Rat   309 SLAEPDFVM-TD----FAKYSRPAQLHIGFQALHQFCAQHNRP---PRPRNEEDATELVT----- 360

  Fly   383 LAVIRGTRIAEEYEKSSRLLPLVEDNELQGNLTAYNFALRAYERFLSECGNIPGECIVEQDIGRL 447
                                                         |::..|......|:||
  Rat   361 ---------------------------------------------LAQAVNARSPPAVQQD---- 376

  Fly   448 KSIAAKMLSDLGMHATISDDVLHEICRYGGAELHAVSAFIGGCAAQEVIKIITKQYKPIDNTFIY 512
                           .:.:|::.::......:|..::|||||.|||||:|..:.::.||.....:
  Rat   377 ---------------NVDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYF 426

  Fly   513 NAI 515
            :|:
  Rat   427 DAL 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	102/523 (20%)
Uba1	NP_001014102.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..46
		Ube1	49..1055	CDD:273603	102/523 (20%)
		2 approximate repeats. /evidence=ECO:0000255	63..611		99/515 (19%)