Protein Alignment APP-BP1 and Atg7

DIOPT Version :10

• Sequence 1: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_008761461.1
• Gene: Atg7 / 312647
• RGDID: 1304817
• Length: 703
• Species: Rattus norvegicus
• Alignment Length: 441
• Identity: 67/441 - (15%)
• Similarity: 116/441 - (26%)
• Gaps: 211/441 - (47%)

  Fly    40 LVNVTAVGCETAKGLVLPGIGGFTVADGSTVK------------EEDLGNNFFLDSSYLGKSKAL 92
            |:....:||..|:.|:..|:...|..|.:.:.            |:.||.         ||.|||
  Rat   356 LLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGG---------GKPKAL 411

  Fly    93 ACMQLLQELNPDVNGDYVDESADFLLANRPNFFDSFDLVIASNLNEQTLLLLAERLWELNVPLIY 157
            |..:.||::.|.||                          ||..|             :::|:
  Rat   412 AAAERLQKIFPGVN--------------------------ASGFN-------------MSIPM-- 435

  Fly   158 CRSLGMLGTIRLQIREHCIVEAHPDNRQFDLRLEHPFDALREHLDGTEVTSKVPWLLVLHKYLNV 222
                                ..||.|
  Rat   436 --------------------PGHPVN--------------------------------------- 441

  Fly   223 WQKQQADGTQTPRNYKEKNQLKETIREEMKADEENYEEAIKAVNTAFGAGQVPKSLKAIFEDDAC 287
                                ..:...|:.:.|.|..||.|.:.:..|           :..|
  Rat   442 --------------------FSDVTMEQARRDVEQLEELIDSHDVIF-----------LLMD--- 472

  Fly   288 EQLNKKSNVFW---IMAKALKHFVIHENEGHLPLPGVLPDMTANTDSYIALQHIYRQQALQDADQ 349
               .::|.  |   ::|.:.:..||:...|.              |:::.::|..::...|.|..
  Rat   473 ---TRESR--WLPTVIAASKRKLVINAALGF--------------DTFVVMRHGLKKPKQQGAGD 518

  Fly   350 VYHKCQEYL------------------------KQLALPADSIDERSVRLICK-EAAGLAVIRGT 389
            :   |..:|                        ..:..|.||..:|::...|. ...|||||.|.
  Rat   519 L---CPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGA 580

  Fly   390 RIAE------EYEKSSRLLPLVEDNELQGNLTAYNFALRAYERFLSECGNI 434
            ...|      ::.:....:....|:.:....|:..........|||...|:
  Rat   581 LAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNV 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	67/441 (15%)
Atg7	XP_008761461.1	E1_like_apg7	11..688	CDD:273590	67/441 (15%)