Protein Alignment APP-BP1 and Uba5

DIOPT Version :9

• Sequence 1: NP_001261699.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001009669.1
• Gene: Uba5 / 300968
• RGDID: 1311702
• Length: 403
• Species: Rattus norvegicus
• Alignment Length: 361
• Identity: 72/361 - (19%)
• Similarity: 116/361 - (32%)
• Gaps: 125/361 - (34%)

  Fly    38 VCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEEDLGNNFFLDSSYLGKSKALACMQLLQELN 102
            |.:|.|..||..||:.|...|||...:.|...|:..:: |..|......|.||..|....|:.:|
  Rat    74 VAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANM-NRLFFQPYQAGMSKVQAAEHTLRSIN 137

  Fly   103 PDV-----------------------NGDYVD-ESADFLLANRPNFFDSFD-------------- 129
            |||                       ||...: :..|.:|    :..|:|:
  Rat   138 PDVLFEVHNYNITTVEHFEHFMNRISNGGLEEGQPVDLVL----SCVDNFEARMAINTACNELGQ 198

  Fly   130 --------------------------------LVIASNLNEQTLLLLAERLWELNVPLIYCRSLG 162
                                            ||:|||::|:|  |..|.:...::|.......|
  Rat   199 TWMESGVSENAVSGHIQLMVPGESACFACAPPLVVASNIDEKT--LKREGVCAASLPTTMGVVAG 261

  Fly   163 ML-----------GTIRLQIREHCIVEAHP-----DNRQFD---LRLEHPFDALREHLDGTEVTS 208
            :|           ||:...:..:.:.:..|     .|.|.|   .|.:......|.....|:.|:
  Rat   262 ILVQNVLKFLLKFGTVSFYLGYNAMQDFFPTMFMKPNPQCDDKNCRKQQEEYKKRAPAQPTQETA 326

  Fly   209 KVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEMKADEENYEEAIKAVNTAFGAGQ 273
            ......|:|:. |.|      |.:.         :.|...||:|..........:.:..|:   .
  Rat   327 PQEEEEVVHED-NEW------GIEL---------VSEVSEEELKNSSGPVPTLPEGITVAY---T 372

  Fly   274 VPK----SLKAIFEDDACEQLNKKSNVFWIMAKALK 305
            |||    |:..:..:|:.|.|..      :||:..|
  Rat   373 VPKKREDSVSEVTVEDSGESLED------LMARMKK 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_001261699.1	APPBP1_RUB	16..522	CDD:238770	72/361 (20%)
		ThiF	17..>171	CDD:223552	44/213 (21%)
Uba5	NP_001009669.1	ThiF_MoeB_HesA_family	50..293	CDD:238386	45/225 (20%)
		ThiF	51..307	CDD:279270	48/239 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..337		6/30 (20%)
		UFM1-interacting sequence (UIS). /evidence=ECO:0000250|UniProtKB:Q9GZZ9	333..345		5/27 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900