DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment APP-BP1 and moc-3

DIOPT Version :9

Sequence 1:	NP_001261699.1	Gene:	APP-BP1 / 39244	FlyBaseID:	FBgn0261112	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_501359.1	Gene:	moc-3 / 177607	WormBaseID:	WBGene00018357	Length:	402	Species:	Caenorhabditis elegans

Alignment Length:	182	Identity:	48/182 - (26%)
Similarity:	78/182 - (42%)	Gaps:	18/182 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SKK----YDRQIRL--WGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKEE 73
            |||    |.||:.:  :|..||..|:...|.:|....:||..|..|...|||...:.|...:..:
Worm    11 SKKDAGRYSRQLLVDDFGVSGQKNLKNLNVLIVGAGGLGCPVATYLGAAGIGTIGIVDYDHISLD 75

  Fly    74 DLGNNFFLDSSYLGKSKALACMQLLQELNPDVNGDYVDESADFLLANRPNFFDSFDLVIASNLNE 138
            :|..........:|||||.|....::..|.|:|....:.|.|  .:|....|.::::|.....|.
Worm    76 NLHRQVAYKEDQVGKSKAQALADNIKLQNSDLNVQVHNTSLD--SSNAMQLFKNYEIVCDCTDNV 138

  Fly   139 QTLLLLAERLWELNVPLIYCRSLGMLGTIRLQIREH--------CIVEAHPD 182
            .|..|:.:....||:||:...:|...|  :|.:..:        |:..:.||
Worm   139 ATRYLINDVCVLLNIPLVSGSALRWDG--QLSVYHYGSDCPCYRCLFPSPPD 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_001261699.1	APPBP1_RUB	16..522	CDD:238770	47/181 (26%)
APP-BP1	NP_001261699.1	ThiF	17..>171	CDD:223552	43/159 (27%)
moc-3	NP_501359.1	PRK07878	8..402	CDD:181156	48/182 (26%)
		ThiF_MoeB_HesA_family	17..246	CDD:238386	45/176 (26%)
		RHOD_ThiF	283..402	CDD:238784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810