DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Irbp18 and Ddit3

DIOPT Version :9

Sequence 1:	NP_001261698.1	Gene:	Irbp18 / 39243	FlyBaseID:	FBgn0036126	Length:	113	Species:	Drosophila melanogaster
Sequence 2:	NP_001103456.1	Gene:	Ddit3 / 29467	RGDID:	62391	Length:	168	Species:	Rattus norvegicus

Alignment Length:	90	Identity:	22/90 - (24%)
Similarity:	44/90 - (48%)	Gaps:	12/90 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ASTSKNSDSPLSPHT-----------DDPAYKEKRKKNNEAVQRT-REKTKKSAEERKKRIDDLR 61
            |..:..|.||.||.:           :|.....|||::.:...|. :::.|:..:|.::::..|.
  Rat    70 AEVTSTSQSPRSPDSSQSSMAQEEEEEDQGRTRKRKQSGQCAARAGKQRMKEKEQENERKVAQLA 134

  Fly    62 KQNDALKVQIETSEKHISTLRDLII 86
            ::|:.||.:||...:.:.|.|..:|
  Rat   135 EENERLKQEIERLTREVETTRRALI 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Irbp18	NP_001261698.1	bZIP_CEBP	24..83	CDD:269841	14/59 (24%)
Irbp18	NP_001261698.1	coiled coil	25..83	CDD:269841	14/58 (24%)
Ddit3	NP_001103456.1	N-terminal. /evidence=ECO:0000250	10..26
		Interaction with TRIB3. /evidence=ECO:0000250	10..18
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..130		13/59 (22%)
		coiled coil	98..152	CDD:269834	12/53 (23%)
		BRLZ	100..160	CDD:197664	15/60 (25%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	100..129		6/28 (21%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	133..147		6/13 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810