Protein Alignment Irbp18 and CEBPB

DIOPT Version :10

• Sequence 1: NP_648434.1
• Gene: Irbp18 / 39243
• FlyBaseID: FBgn0036126
• Length: 113
• Species: Drosophila melanogaster
• Sequence 2: NP_005185.2
• Gene: CEBPB / 1051
• HGNCID: 1834
• Length: 345
• Species: Homo sapiens
• Alignment Length: 86
• Identity: 27/86 - (31%)
• Similarity: 50/86 - (58%)
• Gaps: 6/86 - (6%)

  Fly     2 PAKKRTAASTSKNSDSPLSPHTDDPAYKEKRKKNNEAVQRTREKTKKSAEERKKRIDDLRKQNDA 66
            ||..:..:...|..|.    |:|:  ||.:|::||.||:::|:|.|....|.:.::.:|..:|:.
Human   254 PAPSQVKSKAKKTVDK----HSDE--YKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENER 312

  Fly    67 LKVQIETSEKHISTLRDLIIQ 87
            |:.::|...:.:||||:|..|
Human   313 LQKKVEQLSRELSTLRNLFKQ 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irbp18	NP_648434.1	bZIP_CEBP	24..83	CDD:269841	19/58 (33%)
		coiled coil	25..83	CDD:269841	18/57 (32%)
CEBPB	NP_005185.2	Required for Lys-174 sumoylation	1..24
		Required for MYC transcriptional repression. /evidence=ECO:0000250|UniProtKB:P28033	24..135
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..67
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	79..116
		9aaTAD	116..124
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..178
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..271		4/20 (20%)
		bZIP_CEBPB	264..334	CDD:269860	25/76 (33%)
		coiled coil	271..332	CDD:269860	21/62 (34%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	275..295		9/19 (47%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	297..304		1/6 (17%)