Protein Alignment JIL-1 and SCH9

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_012075.1
• Gene: SCH9 / 856612
• SGDID: S000001248
• Length: 824
• Species: Saccharomyces cerevisiae
• Alignment Length: 737
• Identity: 219/737 - (29%)
• Similarity: 335/737 - (45%)
• Gaps: 174/737 - (23%)

  Fly    15 TSTSRLKNHQHPRESESLAYEEPDQMVRNHLNGQLVANGNGKTR-KNS---------NSETMTNG 69
            :|||.|..:|  ||:.:.||.....:.|..|...::...:..|| |:|         :||.::||
Yeast   157 SSTSSLSINQ--REAAAAAYGPDTDIPRGKLEVTIIEARDLVTRSKDSQPYVVCTFESSEFISNG 219

  Fly    70 KKSKLNTEGSGSGSGKTLNYNNNNNNNNSISATNGQYTNSSSKTTSASARDYTYRETISPPTPPS 134
            .:|        .|:     .||||||||:......|:.|::::.|:..|....:.....
Yeast   220 PES--------LGA-----INNNNNNNNNNQHNQNQHINNNNENTNPDAASQHHNNNSG------ 265

  Fly   135 PPTTNVADIVCISDAESEDGRDPEREYYDQDMEEDEPNGIEIDESSSSLSKAKSNNAAAAAAAAA 199
               .|.:.:..|.                   |..:...:....|||.|.:..|          .
Yeast   266 ---WNGSQLPSIK-------------------EHLKKKPLYTHRSSSQLDQLNS----------C 298

  Fly   200 AAAAAAASKASSSTTPSYAMPTSNS--------TPLDLDNEAHQRDL---EAVTDLKY--YVKLY 251
            ::....:.::|:|::.|...|.::|        |..|:.....:.|:   :|..|..:  .|:||
Yeast   299 SSVTDPSKRSSNSSSGSSNGPKNDSSHPIWHHKTTFDVLGSHSELDISVYDAAHDHMFLGQVRLY 363

  Fly   252 S---------------------DEAVS------------------LNDFKIIRVLGTGAYGRVFL 277
            .                     ||.||                  ..||:::|:||.|.:|:|:.
Yeast   364 PMIHNLAHASQHQWHSLKPRVIDEVVSGDILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQ 428

  Fly   278 VRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTER--VVLEAIQRNPFLVSLHYAFQSSSKLY 340
            |:|   .|..::||||||:|..:|:|.:.| ||..||  :|..|.:.:||:|.|.::||:.:.||
Yeast   429 VKK---KDTQRIYAMKVLSKKVIVKKNEIA-HTIGERNILVTTASKSSPFIVGLKFSFQTPTDLY 489

  Fly   341 LVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVL 405
            ||.|:.:|||||.||.....|.|.|.:.||||:|||||.||...|:|||:|.||||||..|:|.|
Yeast   490 LVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIAL 554

  Fly   406 SDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATS 470
            .||||||   |:.:.|.::||||.||:|||:: ....|:...||:||:|||.||:..|.|||...
Yeast   555 CDFGLSK---ADLKDRTNTFCGTTEYLAPELL-LDETGYTKMVDFWSLGVLIFEMCCGWSPFFAE 615

  Fly   471 DGQVQQSEIS-RRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGIN 534
            :.|....:|: .:::..:.::    |...|.||..:|.:|||.|||... |..|::.||||..|:
Yeast   616 NNQKMYQKIAFGKVKFPRDVL----SQEGRSFVKGLLNRNPKHRLGAID-DGRELRAHPFFADID 675

  Fly   535 WQELRTKRRKAPYKPTLTAEDDVQNFSNEFT--------------DQVPEDPECDAPPSRIRLFR 585
            |:.|:.|:...|:||.|.:|.|..||..|||              ...|..|...|.      |.
Yeast   676 WEALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMNKHQPMMTATPLSPAMQAK------FA 734

  Fly   586 GYTYVAPEHLEQMRRDNHCEIQ--YFN------TGLQNIPCRPD----------DLELG---TRT 629
            |:|:|....:::...:|...:|  ||.      .|..|:|  ||          |:..|   .:.
Yeast   735 GFTFVDESAIDEHVNNNRKFLQNSYFMEPGSFIPGNPNLP--PDEDVIDDDGDEDINDGFNQEKN 797

  Fly   630 SNGAYGTCHFVVDSSTDLVFLA 651
            .|.::....|..|...|..|::
Yeast   798 MNNSHSQMDFDGDQHMDDEFVS 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	120/269 (45%)
		S_TK_X	532..591	CDD:214529	21/72 (29%)
		S_TKc	632..886	CDD:214567	4/20 (20%)
SCH9	NP_012075.1	YPK1_N_like	181..407	CDD:212165	49/276 (18%)
		STKc_Sck1_like	418..738	CDD:270738	140/338 (41%)