Protein Alignment JIL-1 and CBK1

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_014238.3
• Gene: CBK1 / 855561
• SGDID: S000005105
• Length: 756
• Species: Saccharomyces cerevisiae
• Alignment Length: 731
• Identity: 200/731 - (27%)
• Similarity: 306/731 - (41%)
• Gaps: 190/731 - (25%)

  Fly     4 LQKQNYEILSGTSTSRLKN-------HQHPRESESLAYEEPDQMVRNHLNGQLVANGNGKTRKNS 61
            ||::...:.||.:.....|       |.:...|..:....|..|             .|..|.|:
Yeast    71 LQRETGNLGSGFTDVPALNYPATPPPHNNYAASNQMINTPPPSM-------------GGLYRHNN 122

  Fly    62 NSETMTNGKKSKLNTEGSGSGSGK-----------TLNYNNNNNNNNSIS--------ATNGQYT 107
            ||::|..        .|:|||:.:           ...||.|.|.::|.|        .:||.|
Yeast   123 NSQSMVQ--------NGNGSGNAQLPQLSPGQYSIESEYNQNLNGSSSSSPFHQPQTLRSNGSY- 178

  Fly   108 NSSSKTTSASARDYTYRETISPPTPPSPPTTNVADIVCISDAESEDGRDPER--EYYDQDMEEDE 170
            :|..::..:..|....:|             ||.....:|.|:.::.|..::  :|..|..::.:
Yeast   179 SSGLRSVKSFQRLQQEQE-------------NVQVQQQLSQAQQQNSRQQQQQLQYQQQQQQQQQ 230

  Fly   171 PNGIEI---------DESSSSLSKAKSNNAAAA------------AAAAAAAAAAAASKASS--S 212
            ...::|         .:.|.|..::..||...:            .......|||...|..:  .
Yeast   231 QQHMQIQQQQQQQQQQQQSQSPVQSGFNNGTISNYMYFERRPDLLTKGTQDKAAAVKLKIENFYQ 295

  Fly   213 TTPSYAMPTSN-----STPLDLDNEAHQRDLEAVTDL----KYYVKLYSDEAVSLNDFKIIRVLG 268
            ::..||:..:.     .|.|...|.:.:|....::.|    ..:::|.... :||.||..::|:|
Yeast   296 SSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGKKESQFLRLRRTR-LSLEDFHTVKVIG 359

  Fly   269 TGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAF 333
            .||:|.|.||:|   .|.||:||||.|.|..:.:|.:.| |.|.||.|| |...:|::|||:|:|
Yeast   360 KGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYKKDQLA-HVKAERDVL-AGSDSPWVVSLYYSF 419

  Fly   334 QSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLD 398
            |.:..|||:::|..||:|.|.|...:.|.|...|.|:||.:||:|.:|:||.|:||||.:|||:|
Yeast   420 QDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILID 484

  Fly   399 GEGHIVLSDFGLS-------------KI------------------------------------L 414
            ..|||.|||||||             |:                                    |
Yeast   485 IRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISL 549

  Fly   415 TAENEYR-----------AHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFA 468
            |..|..:           |:|..||.:|:||||...  .|:....||||:|.:.:|.|.|..||.
Yeast   550 TMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLY--QGYGQECDWWSLGAIMYECLIGWPPFC 612

  Fly   469 TSDGQVQQSEISRRIQK-EQPM-IPSS--FSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPF 529
            :...|    |..|:|.. ||.: .|..  .|..|.|.:.::|....:|.  |.|..|.|||.|||
Yeast   613 SETPQ----ETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRL--GRHGGADEIKSHPF 671

  Fly   530 FNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPEC---------------DAPPS 579
            |.|::|..:|  :.:|||.|.|::..|.:.|..:..:.||:.|..               .||..
Yeast   672 FRGVDWNTIR--QVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVK 734

  Fly   580 RIRLFRGYTYVAPEHL 595
            ....|.||||...::|
Yeast   735 EDLPFIGYTYSRFDYL 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	120/330 (36%)
		S_TK_X	532..591	CDD:214529	20/73 (27%)
		S_TKc	632..886	CDD:214567
CBK1	NP_014238.3	MobB_CBK1	269..341	CDD:439268	11/71 (15%)
		STKc_NDR_like_fungal	350..748	CDD:270778	142/412 (34%)