DRSC/TRiP Functional Genomics Resources

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Protein Alignment JIL-1 and YPK1

DIOPT Version :9

Sequence 1:NP_001261697.1 Gene:JIL-1 / 39241 FlyBaseID:FBgn0020412 Length:1207 Species:Drosophila melanogaster
Sequence 2:NP_012796.1 Gene:YPK1 / 853733 SGDID:S000001609 Length:680 Species:Saccharomyces cerevisiae


Alignment Length:678 Identity:201/678 - (29%)
Similarity:313/678 - (46%) Gaps:125/678 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 SGTSTSRLKNHQHPRESESLAYEEPDQMVRNHLNGQLVANGNGKTRKNSNSETMTNGKKSKLNTE 77
            ||...|..|..|  :.:::.|.|....:.|:.|:.:...|       .|||..:      .:...
Yeast    22 SGFFHSSKKEEQ--QNNQATAGEHDASITRSSLDRKGTIN-------PSNSSVV------PVRVS 71

  Fly    78 GSGSGSGKTLNYNNNNNNNNSISATN----------GQYTNSSSKTTSASARDYTYRETISP-PT 131
            ...|.|..|:..:|..|:.|:.|:.|          |...:::|.:...:.:.|...:.|.| |.
Yeast    72 YDASSSTSTVRDSNGGNSENTNSSQNLDETANIGSTGTPNDATSSSGMMTIKVYNGDDFILPFPI 136

  Fly   132 PPS-------------PPTTNVADIVCISDAESEDGRDPEREYYDQDMEEDE------PNGIEID 177
            ..|             ||...::..|....|:....:...:...|:|:...|      |:.|.: 
Yeast   137 TSSEQILNKLLASGVPPPHKEISKEVDALIAQLSRVQIKNQGPADEDLISSESAAKFIPSTIML- 200

  Fly   178 ESSSSLSKAK------SNNAAAAAAAAAAAAAAAASKASS---------------STTPSYAMPT 221
            ..||:|:...      .|..|...|.....|....:|.|:               :..||..:|:
Yeast   201 PGSSTLNPLLYFTIEFDNTVATIEAEYGTIAKPGFNKISTFDVTRKLPYLKIDVFARIPSILLPS 265

  Fly   222 SN-STPLDLDNEAHQRDLEAVT------------------DLKYYVKLYS--------------- 252
            .. ...:.|.:|..|...:.:.                  |....::||:               
Yeast   266 KTWQQEMGLQDEKLQTIFDKINSNQDIHLDSFHLPINLSFDSAASIRLYNHHWITLDNGLGKINI 330

  Fly   253 --------DEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEH 309
                    ::.:|::||.:::|:|.|::|:|..|||   .|..|:||:|.:.|..:|.|.:.. |
Yeast   331 SIDYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRK---KDTQKVYALKAIRKSYIVSKSEVT-H 391

  Fly   310 TKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVV 374
            |..||.||..:. .||:|.|.::|||..|||.||.|.||||||.||.....|:.||.|.|.||::
Yeast   392 TLAERTVLARVD-CPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELL 455

  Fly   375 LALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRT 439
            .||:.||:|.::|||:|.||||||.:|||.|.||||.| |..:::.:..:||||.||:|||::. 
Yeast   456 CALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCK-LNMKDDDKTDTFCGTPEYLAPELLL- 518

  Fly   440 GPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLK 504
             ..|:..|||||::|||.:|:|||..|:...|    ..::.::|.:|..:.|..|..:|:|.::.
Yeast   519 -GLGYTKAVDWWTLGVLLYEMLTGLPPYYDED----VPKMYKKILQEPLVFPDGFDRDAKDLLIG 578

  Fly   505 MLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVP 569
            :|.::|.||||.|  .|.||:.||||:.::|:.|..|....||||.::...|..||..|||.:.|
Yeast   579 LLSRDPTRRLGYN--GADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKP 641

  Fly   570 EDPECD--APPSRIRLFRGYTYVAPEHL 595
            .|...|  ...|..:.|.|:|||..|.|
Yeast   642 IDSVVDEYLSESVQKQFGGWTYVGNEQL 669

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
JIL-1NP_001261697.1 S_TKc 261..530 CDD:214567 118/268 (44%)
STKc_MSK_N 266..533 CDD:270735 119/266 (45%)
S_TK_X 532..591 CDD:214529 21/60 (35%)
S_TKc 632..886 CDD:214567
PKc_like 632..885 CDD:304357
YPK1NP_012796.1 YPK1_N_like 116..342 CDD:212165 32/226 (14%)
PKc_like 352..663 CDD:419665 138/324 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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