DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment JIL-1 and S6K2

DIOPT Version :9

Sequence 1:	NP_001261697.1	Gene:	JIL-1 / 39241	FlyBaseID:	FBgn0020412	Length:	1207	Species:	Drosophila melanogaster
Sequence 2:	NP_001327294.1	Gene:	S6K2 / 820019	AraportID:	AT3G08720	Length:	471	Species:	Arabidopsis thaliana

Alignment Length:	429	Identity:	170/429 - (39%)
Similarity:	242/429 - (56%)	Gaps:	43/429 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 NAAAAAAAAAAAAAAAASKASSSTTPSYAMPTSNSTPLDLDNEAHQRDLEAVTDLKYYVKLYS-- 252
            |:..|...|....|...|::.|...||  :..|:|..:   |:...|:.|...||...|:..|
plant    52 NSEEACDVAYDEPAVVYSRSHSLVGPS--LVVSHSLKM---NKLTLRETEDSVDLVECVEGESIK 111

  Fly   253 --DE------------------AVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNK 297
              ||                  .|.:.||::::|:|.||:|:|:.|||   .|..::|||||:.|
plant   112 ENDEFSGNDDTDSEKSPEEVSGVVGIEDFEVLKVVGQGAFGKVYQVRK---KDTSEIYAMKVMRK 173

  Fly   298 ITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFE 362
            ..:|:|.. ||:.|.||.:|..|. :||:|.|.|:||:..:|||||||.|||.||..|||...|.
plant   174 DKIVEKNH-AEYMKAERDILTKID-HPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFR 236

  Fly   363 ESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCG 427
            |...|||.||:|.|:..||:.||::||:|.||||:|.:||::|:||||:|  ..|...|::|.||
plant   237 EDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAK--EFEENTRSNSMCG 299

  Fly   428 TLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPS 492
            |.|||||||:|  ..|||.|.||||||:|.:|:|||..||..|.|::||     :|.|::..:|.
plant   300 TTEYMAPEIVR--GKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQ-----KIVKDKIKLPQ 357

  Fly   493 SFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDV 557
            ..|..|...:..:|:|.|:||||.....|.|||:|.:|..|||::|..:..:..:||.::....:
plant   358 FLSNEAHALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCI 422

  Fly   558 QNFSNEFTDQVPEDPECDAPPS--RIRLFRGYTYVAPEH 594
            .||...:||....|....:|.|  :...|..:|||.|.|
plant   423 ANFDKCWTDMSVLDSPASSPNSDAKANPFTNFTYVRPPH 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_001261697.1	S_TKc	261..530	CDD:214567	129/268 (48%)
		STKc_MSK_N	266..533	CDD:270735	129/266 (48%)
		S_TK_X	532..591	CDD:214529	16/60 (27%)
		S_TKc	632..886	CDD:214567
		PKc_like	632..885	CDD:304357
S6K2	NP_001327294.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1132245at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880