DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JIL-1 and si:ch211-195b13.1

DIOPT Version :9

Sequence 1:	NP_001261697.1	Gene:	JIL-1 / 39241	FlyBaseID:	FBgn0020412	Length:	1207	Species:	Drosophila melanogaster
Sequence 2:	NP_001070770.2	Gene:	si:ch211-195b13.1 / 768159	ZFINID:	ZDB-GENE-030131-7626	Length:	423	Species:	Danio rerio

Alignment Length:	371	Identity:	144/371 - (38%)
Similarity:	207/371 - (55%)	Gaps:	24/371 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 NEAHQRDLEAVTDLKYYVKLYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKL-YAMKV 294
            ||....:|..:|..:  ..|..:..:..:||..::::|.|::|:|.    |.||...:| ||:||
Zfish    63 NEELDENLLCLTHPR--SSLAEETQIKPSDFDYLKIIGKGSFGKVL----LARHKENELYYAVKV 121

  Fly   295 LNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSE 359
            |.| .::.|:|..:|...||.||....::||||.|||:||::.|||.|||:.||||||.||....
Zfish   122 LQK-KIIMKKKEQKHIMAERSVLMKNIKHPFLVGLHYSFQTTDKLYFVLDYVNGGELFYHLQRER 185

  Fly   360 NFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHS 424
            .|.|.|.|.|.||:..||..||.|.|:|||:|.||||||.:|||||:||||.|.....|. ...:
Zfish   186 VFLEPRARFYAAEIASALGYLHSLHIVYRDLKPENILLDSQGHIVLTDFGLCKEGLDPNG-TTTT 249

  Fly   425 FCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPM 489
            ||||.||:|||:::  ...:|..||||.:|.:.||:|.|..||.:.:    .:|:...|..:..:
Zfish   250 FCGTPEYLAPEVLQ--KQAYDRTVDWWCLGSVLFEMLYGLPPFYSRN----TAEMYNNILHKPLV 308

  Fly   490 IPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAE 554
            :..:.|...||.:..:|.|:..:|||... |..|:|.|.||:.|||.:|..||...|:.||:|..
Zfish   309 LKPNVSNAGRDLLEGLLHKDRTKRLGSKD-DFLELKFHSFFSPINWDDLMAKRIVPPFIPTVTGP 372

  Fly   555 DDVQNFSNEFTDQVPEDPECDAP----PSRIR----LFRGYTYVAP 592
            .|:::|..|||........|:..    .|.:|    .|.|::|..|
Zfish   373 TDLRHFDPEFTHLPVSTSLCNTDNLHVTSSVREAAGAFPGFSYGPP 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_001261697.1	S_TKc	261..530	CDD:214567	114/269 (42%)
		STKc_MSK_N	266..533	CDD:270735	115/267 (43%)
		S_TK_X	532..591	CDD:214529	21/66 (32%)
		S_TKc	632..886	CDD:214567
		PKc_like	632..885	CDD:304357
si:ch211-195b13.1	NP_001070770.2	S_TKc	91..348	CDD:214567	114/269 (42%)
si:ch211-195b13.1	NP_001070770.2	STKc_SGK	95..415	CDD:270727	135/332 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910