Protein Alignment JIL-1 and Rps6ka5

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_705815.1
• Gene: Rps6ka5 / 73086
• MGIID: 1920336
• Length: 863
• Species: Mus musculus
• Alignment Length: 745
• Identity: 306/745 - (41%)
• Similarity: 410/745 - (55%)
• Gaps: 121/745 - (16%)

  Fly   254 EAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLE 318
            |.|.:.:|::::||||||||:||||||::.||||||||||||.|.|:|||.||.|||:|||.|||
Mouse    41 EKVGIENFELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 105

  Fly   319 AIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQL 383
            .|:::||||:||||||:.:||:|:||:.|||||||||...|.|.|..|::|:.|:|||||.||:|
Mouse   106 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKL 170

  Fly   384 GIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAV 448
            |||||||||||||||..||:||:||||||...|:...||:|||||:|||||:|:|.|..|||.||
Mouse   171 GIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAV 235

  Fly   449 DWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRR 513
            ||||:|||.:|||||||||.....:..|:||||||.|.:|..|...|..|:|.:.::|.|:||:|
Mouse   236 DWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSTVAKDLLQRLLMKDPKKR 300

  Fly   514 LGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPP 578
            ||...|||.|||||.||..|.|.:|..|:..||:||.:..|.||.||:.|||:..|.......|.
Mouse   301 LGCGPRDAEEIKEHLFFEKIKWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQ 365

  Fly   579 SRIRLFRGYTYVAPEHLEQMRRDNHCEIQYFNTGLQNIPCRPD-------------------DLE 624
            |..|||:||::|||..|.: |.....:...|:.|:.    ||.                   ||:
Mouse   366 SSERLFQGYSFVAPSILFK-RNAAVIDPLQFHMGVD----RPGVTNVARSAMMKDSPFYQHYDLD 425

  Fly   625 LGTR-TSNGAYGTCHFVVDSSTDLVFLAKIIP--LSKFRPSEVDALISCALDTTNHKNIVSYHGT 686
            |..: ...|::..|...|...|:..|..|||.  :......|:.||..|    ..|.|||..|..
Mouse   426 LKDKPLGEGSFSICRKCVHKKTNQAFAVKIISKRMEANTQKEITALKLC----EGHPNIVKLHEV 486

  Fly   687 FREK-------------CE-------------------TW------------------------- 694
            |.::             |.                   ||
Mouse   487 FHDQVAASAQPPGQVVLCSLLLLALLFNRSLTRKPVTWTWLVHSTSQLPPLPPPMPEIVLFILLS 551

  Fly   695 --------IVMEYLSGPELTASIR----MDEDSCREIFLQLVMAVRHIHSKHFIHGDLKPENIMF 747
                    :|||.|:|.||...|:    ..|.....|..:||.||.|:|....:|.||||||::|
Mouse   552 DNGQLHTFLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLF 616

  Fly   748 ENREDR-TVKLIDFGSACYNNRFKSWKDKPR----YTLDYAPPEMLADANLVTYSPAVDIYGLGA 807
            .:..|. .:|:||||.|    |.|...::|.    :||.||.||:|....   |..:.|::.||.
Mouse   617 TDENDNLEIKVIDFGFA----RLKPPDNQPLKTPCFTLHYAAPELLTHNG---YDESCDLWSLGV 674

  Fly   808 TLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPA 872
            .|||||.|..|::.::..:..::|.  |:.|::::|.|:.....|::.|...:.|:...|..||.
Mouse   675 ILYTMLSGQVPFQSHDRSLTCTSAV--EIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPN 737

  Fly   873 DRPTLSDILDSEWLQYGSN-------DPDV 895
            .|..:|.:..:||||.||.       .||:
Mouse   738 KRLKMSGLRYNEWLQDGSQLSSNPLMTPDI 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	173/266 (65%)
		S_TK_X	532..591	CDD:214529	24/58 (41%)
		S_TKc	632..886	CDD:214567	87/329 (26%)
Rps6ka5	NP_705815.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		Protein Kinases, catalytic domain	47..379	CDD:473864	199/331 (60%)
		STKc_MSK1_C	417..791	CDD:271081	97/364 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	805..863