DRSC/TRiP Functional Genomics Resources

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Protein Alignment JIL-1 and Rps6kb1

DIOPT Version :10

Sequence 1:NP_648432.1 Gene:JIL-1 / 39241 FlyBaseID:FBgn0020412 Length:1207 Species:Drosophila melanogaster
Sequence 2:NP_001107806.1 Gene:Rps6kb1 / 72508 MGIID:1270849 Length:525 Species:Mus musculus


Alignment Length:341 Identity:157/341 - (46%)
Similarity:223/341 - (65%) Gaps:10/341 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly   261 FKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPF 325
            |:::||||.|.||:||.|||:|..:.||::|||||.|..:|:..|...|||.||.:||.: ::||
Mouse    91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV-KHPF 154

  Fly   326 LVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDI 390
            :|.|.||||:..||||:|::.:|||||..|.....|.|.....|:||:.:||..|||.||||||:
Mouse   155 IVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDL 219

  Fly   391 KLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGV 455
            |.|||:|:.:||:.|:||||.|....:... .|:||||:|||||||:...  ||:.||||||:|.
Mouse   220 KPENIMLNHQGHVKLTDFGLCKESIHDGTV-THTFCGTIEYMAPEILMRS--GHNRAVDWWSLGA 281

  Fly   456 LTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRD 520
            |.:::||||.||.   |:.::..|. :|.|.:..:|...:..|||.:.|:|::|...|||....|
Mouse   282 LMYDMLTGAPPFT---GENRKKTID-KILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGD 342

  Fly   521 ASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDA--PPSRIRL 583
            |.|::.||||..|||:||..::.:.|:||.|.:|:||..|.::||.|.|.|...|:  ..|..::
Mouse   343 AGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQV 407

  Fly   584 FRGYTYVAPEHLEQMR 599
            |.|:|||||..||.::
Mouse   408 FLGFTYVAPSVLESVK 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
JIL-1NP_648432.1 STKc_MSK_N 266..533 CDD:270735 126/266 (47%)
S_TK_X 532..591 CDD:214529 24/60 (40%)
S_TKc 632..886 CDD:214567
Rps6kb1NP_001107806.1 TOS motif 28..32
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 32..54
STKc_p70S6K 94..416 CDD:270736 152/329 (46%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 380..399 7/18 (39%)
Autoinhibitory domain 424..525 157/341 (46%)
Blue background indicates that the domain is not in the aligned region.

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