Protein Alignment JIL-1 and Rps6ka4

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_064308.2
• Gene: Rps6ka4 / 56613
• MGIID: 1930076
• Length: 773
• Species: Mus musculus
• Alignment Length: 744
• Identity: 306/744 - (41%)
• Similarity: 413/744 - (55%)
• Gaps: 63/744 - (8%)

  Fly   253 DEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVL 317
            :|.||:.:|.:::||||||||:||||||...||||||||||||.|..:||:.||.|||:|||.||
Mouse    25 EEKVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVL 89

  Fly   318 EAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQ 382
            |.:::.||||:||||||:.:||:|:||:.:|||:|||||..:.|:|:.||||..|:|||||.||:
Mouse    90 ELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHK 154

  Fly   383 LGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSA 447
            |||||||:||||:|||.||||||:||||||....|.:.|..|||||:|||||||||: ..||..|
Mouse   155 LGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRS-KAGHGKA 218

  Fly   448 VDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKR 512
            |||||:|:|.||||||||||.....:..|:|:||||.|..|..|......|:|.:.::|.|:||:
Mouse   219 VDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPLRIGPVAQDLLQRLLCKDPKK 283

  Fly   513 RLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVP-EDPECDA 576
            |||...:.|.|:|.||||.|::|..|..::..||::|.:.:|.||.||:.|||...| ..|....
Mouse   284 RLGAGPQGAQEVKSHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPAGSP 348

  Fly   577 PPSRIRLFRGYTYVAP----EHLEQMRRDNHCEIQYFNTG-------------LQNIPCRPDDLE 624
            ||...|:|:||::|||    :|...:..|   .:|....|             :|:.|.. ...|
Mouse   349 PPGDPRIFQGYSFVAPSILFDHNNAVMAD---VLQAPGAGYRPGRAAVARSAMMQDSPFF-QQYE 409

  Fly   625 LGTR---TSNGAYGTCHFVVDSSTDLVFLAKIIP--LSKFRPSEVDALISCALDTTNHKNIVSYH 684
            |..|   ...|::..|.......:...|..||:.  |.:....||.||..|    .:|.|:|:.|
Mouse   410 LDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEENTQREVAALRLC----QSHPNVVNLH 470

  Fly   685 GTFREKCETWIVMEYLSGPELTASIR----MDEDSCREIFLQLVMAVRHIHSK-HFIHGDLKPEN 744
            ....::..|::|:|.|.|.||...||    ..|....:|...||.||..:|.: ..:|.||||||
Mouse   471 EVLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPEN 535

  Fly   745 IMF-ENREDRTVKLIDFGSACYNNRFKSWK-----DKPRYTLDYAPPEMLADANLVTYSPAVDIY 803
            |:: ::.....||:||||.|    |.:...     ..|.:||.||.||:||...   |..:.|::
Mouse   536 ILYADDTPGAPVKIIDFGFA----RLRPQSPAEPMQTPCFTLQYAAPELLAQQG---YDESCDLW 593

  Fly   804 GLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQ 868
            .||..||.||.|..|::........|.||  |:..::|.|.|:.....|:..|...:.||...|.
Mouse   594 SLGVILYMMLSGQVPFQGASGQGGQSQAA--EIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLT 656

  Fly   869 RDPADRPTLSDILDSEWLQYGSNDPDVDIILPQQMVVDLSEDTMEQPTGGMFDDQQQLEFMHDKS 933
            .|||.|..|..:..|.|||.||......:..|     |:.|.:......|:     ...||....
Mouse   657 VDPAKRLKLEGLRSSSWLQDGSARSSPPLRTP-----DVLESSGPAVRSGL-----NATFMAFNR 711

  Fly   934 AEDEGITLVS-EPMDTTVATHESRRNAAA 961
            .:.||..|.| |.........:..|:|||
Mouse   712 GKREGFFLKSVENAPLAKRRKQKLRSAAA 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	164/266 (62%)
		S_TK_X	532..591	CDD:214529	22/59 (37%)
		S_TKc	632..886	CDD:214567	84/266 (32%)
Rps6ka4	NP_064308.2	STKc_MSK2_N	32..364	CDD:270765	188/332 (57%)
		STKc_MSK2_C	404..714	CDD:271082	98/333 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	674..696		7/26 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	728..773		4/13 (31%)