DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JIL-1 and sgk2b

DIOPT Version :9

Sequence 1:	NP_001261697.1	Gene:	JIL-1 / 39241	FlyBaseID:	FBgn0020412	Length:	1207	Species:	Drosophila melanogaster
Sequence 2:	XP_009290615.1	Gene:	sgk2b / 559050	ZFINID:	ZDB-GENE-060929-44	Length:	409	Species:	Danio rerio

Alignment Length:	336	Identity:	137/336 - (40%)
Similarity:	195/336 - (58%)	Gaps:	15/336 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 VSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAI 320
            ||..||..::|:|||::|:|||.   |..:.||.||:|||.| .::..||...:...|..||...
Zfish    77 VSAGDFDYLKVIGTGSFGKVFLA---THRENGKYYAVKVLQK-HIILTRKEERNVMCEHRVLLKT 137

  Fly   321 QRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGI 385
            ..:||||.||::||:..:||||||:|.|||||.||.....|.|:|.|.|.||:..||..||.|.|
Zfish   138 LNHPFLVKLHFSFQTKERLYLVLDYACGGELFYHLQREGVFGEARARFYAAEMACALGYLHSLKI 202

  Fly   386 IYRDIKLENILLDGEGHIVLSDFGLSKI-LTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVD 449
            :|||:|.||||||..||:||:||||.|. ::.....|  :||||.||:|||::.  ...:|..||
Zfish   203 VYRDLKPENILLDSAGHVVLTDFGLCKEGMSGRGTTR--TFCGTPEYLAPEVLL--QEEYDRTVD 263

  Fly   450 WWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRL 514
            ||.:|.:..|:|.|..||..:|    :.|:.|.|..:...:.:..|:.|||.:.::|.::..:||
Zfish   264 WWGLGAVLHEMLYGLPPFYNAD----RLEMLRNIIYQPLALKAGVSSAARDLLKRLLNRDRAKRL 324

  Fly   515 GGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPPS 579
            |.. ||..|::.|.||:.|.|.||..|:.:.||.|.|:...|:.|....|| ::|......|...
Zfish   325 GAK-RDLIELQSHAFFSPIQWDELVAKKIQPPYVPVLSGPGDLTNIDPRFT-ELPVPHSLGACED 387

  Fly   580 RIRLFRGYTYV 590
            ....|.|:|::
Zfish   388 HGANFPGFTFI 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_001261697.1	S_TKc	261..530	CDD:214567	114/269 (42%)
		STKc_MSK_N	266..533	CDD:270735	115/267 (43%)
		S_TK_X	532..591	CDD:214529	18/59 (31%)
		S_TKc	632..886	CDD:214567
		PKc_like	632..885	CDD:304357
sgk2b	XP_009290615.1	S_TKc	82..339	CDD:214567	114/269 (42%)
sgk2b	XP_009290615.1	PKc_like	86..398	CDD:304357	133/325 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000