Protein Alignment JIL-1 and PRKACB

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_891993.1
• Gene: PRKACB / 5567
• HGNCID: 9381
• Length: 398
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 124/316 - (39%)
• Similarity: 187/316 - (59%)
• Gaps: 23/316 - (7%)

  Fly   258 LNDFKIIRVLGTGAYGRVFLVRKLTRHDA-GKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQ 321
            |.||:..:.||||::|||.||    :|.| .:.||||:|:|..|| |.|..|||..|:.:|:|:
Human    88 LEDFERKKTLGTGSFGRVMLV----KHKATEQYYAMKILDKQKVV-KLKQIEHTLNEKRILQAV- 146

  Fly   322 RNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGII 386
            ..||||.|.|||:.:|.||:|:::..|||:|:||.....|.|...|.|.|::||..|.||.|.:|
Human   147 NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLI 211

  Fly   387 YRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWW 451
            |||:|.||:|:|.:|:|.::|||.:|.:..    |..:.|||.||:|||||.:  .|::.|||||
Human   212 YRDLKPENLLIDHQGYIQVTDFGFAKRVKG----RTWTLCGTPEYLAPEIILS--KGYNKAVDWW 270

  Fly   452 SVGVLTFELLTGASP-FATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLG 515
            ::|||.:|:..|..| ||....|:.:..:|.:::     .||.||::.:|.:..:|:.:..:|.|
Human   271 ALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR-----FPSHFSSDLKDLLRNLLQVDLTKRFG 330

  Fly   516 GNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPED 571
            ......|:||.|.:|...:|..:..::.:||:.|......|..||.    |...||
Human   331 NLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFD----DYEEED 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	111/268 (41%)
		S_TK_X	532..591	CDD:214529	10/40 (25%)
		S_TKc	632..886	CDD:214567
PRKACB	NP_891993.1	STKc_PKA	89..378	CDD:271111	120/309 (39%)