Protein Alignment JIL-1 and PDPK1

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: XP_011520823.1
• Gene: PDPK1 / 5170
• HGNCID: 8816
• Length: 590
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 110/307 - (35%)
• Similarity: 175/307 - (57%)
• Gaps: 16/307 - (5%)

  Fly   260 DFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNP 324
            |||..::||.|::..|.|.|:|.   ..:.||:|:|.|..::::.|....|: ||.|:..:. :|
Human   115 DFKFGKILGEGSFSTVVLARELA---TSREYAIKILEKRHIIKENKVPYVTR-ERDVMSRLD-HP 174

  Fly   325 FLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRD 389
            |.|.|::.||...|||..|.:|..|||..::....:|:|:..|.|.||:|.|||.||..|||:||
Human   175 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 239

  Fly   390 IKLENILLDGEGHIVLSDFGLSKILTAEN-EYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSV 453
            :|.|||||:.:.||.::|||.:|:|:.|: :.||:||.||.:|::||::........|  |.|::
Human   240 LKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSS--DLWAL 302

  Fly   454 GVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNH 518
            |.:.::|:.|..||...:..:    |.::|.|.:...|..|...|||.|.|:|..:..:|||...
Human   303 GCIIYQLVAGLPPFRAGNEYL----IFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEE 363

  Fly   519 RDA-SEIKEHPFFNGINWQEL--RTKRRKAPYKPTLTAEDDVQNFSN 562
            .:. ..:|.||||..:.|:.|  :|..:...|.|.: :|||...:.|
Human   364 MEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAM-SEDDEDCYGN 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	98/268 (37%)
		S_TK_X	532..591	CDD:214529	9/33 (27%)
		S_TKc	632..886	CDD:214567
PDPK1	XP_011520823.1	STKc_PDK1	114..376	CDD:270733	99/271 (37%)
		PH_PDK1	475..581	CDD:241293