DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JIL-1 and rps6kb1b

DIOPT Version :9

Sequence 1:	NP_001261697.1	Gene:	JIL-1 / 39241	FlyBaseID:	FBgn0020412	Length:	1207	Species:	Drosophila melanogaster
Sequence 2:	NP_998241.1	Gene:	rps6kb1b / 406349	ZFINID:	ZDB-GENE-040426-2038	Length:	502	Species:	Danio rerio

Alignment Length:	341	Identity:	151/341 - (44%)
Similarity:	220/341 - (64%)	Gaps:	10/341 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 FKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPF 325
            |:::||||.|.||:||.|||::....||::|||||.|..:|:..|...|||.||.:||.: ::||
Zfish    65 FELLRVLGKGGYGKVFQVRKVSGAATGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV-KHPF 128

  Fly   326 LVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDI 390
            :|.|.||||:..||||:|::.:|||||..|.....|.|.....|:||:.:||..|||.||||||:
Zfish   129 IVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDL 193

  Fly   391 KLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGV 455
            |.|||:|:.:||:.|:||||.|....:... .|:||||:|||||||:...  ||:.||||||:|.
Zfish   194 KPENIMLNNQGHVKLTDFGLCKESIHDGTV-THTFCGTIEYMAPEILMRS--GHNRAVDWWSLGA 255

  Fly   456 LTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRD 520
            |.:::||||.||.   |:.::..|. :|.|.:..:|...:..|||.:.::|:::...|||....|
Zfish   256 LMYDMLTGAPPFT---GENRKKTID-KILKCKLNLPPYLTQEARDLLKRLLKRSASSRLGAGPGD 316

  Fly   521 ASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDA--PPSRIRL 583
            |:|::.||||..:||.:|..::.:.|:||.|...:||..|.::||.|.|.|...|:  ..|..::
Zfish   317 ATEVQTHPFFRHVNWDDLLARKVEPPFKPFLQFAEDVSQFDSKFTSQTPVDSPDDSTLSESANQV 381

  Fly   584 FRGYTYVAPEHLEQMR 599
            |.|:|||||..||.::
Zfish   382 FLGFTYVAPSVLENIK 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_001261697.1	S_TKc	261..530	CDD:214567	123/268 (46%)
		STKc_MSK_N	266..533	CDD:270735	123/266 (46%)
		S_TK_X	532..591	CDD:214529	21/60 (35%)
		S_TKc	632..886	CDD:214567
		PKc_like	632..885	CDD:304357
rps6kb1b	NP_998241.1	S_TKc	65..326	CDD:214567	123/268 (46%)
rps6kb1b	NP_998241.1	STKc_p70S6K	68..390	CDD:270736	146/329 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573232
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1132245at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850