DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment JIL-1 and Stk32a

DIOPT Version :9

Sequence 1:	NP_001261697.1	Gene:	JIL-1 / 39241	FlyBaseID:	FBgn0020412	Length:	1207	Species:	Drosophila melanogaster
Sequence 2:	NP_001178823.1	Gene:	Stk32a / 364858	RGDID:	1308338	Length:	397	Species:	Rattus norvegicus

Alignment Length:	399	Identity:	121/399 - (30%)
Similarity:	204/399 - (51%)	Gaps:	64/399 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 LYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTER 314
            |..:|.|:.:.|:|:|.:|.|::|:|.:|:|   :|..|:||||.:||...|::.:.....| |.
  Rat    12 LDENEDVNFDHFEILRAIGKGSFGKVCIVQK---NDTKKMYAMKYMNKQKCVERNEVRNVFK-EL 72

  Fly   315 VVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQ 379
            .:::.:: :||||:|.|:||....:::|:|...||:|..||..:.:|:|..|:::|.|:.:||:.
  Rat    73 QIMQGLE-HPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMALDY 136

  Fly   380 LHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRT-GPPG 443
            |....||:||:|.:|||||..||:.::||.::.:|..|.  |..:..||..|||||:..: ...|
  Rat   137 LQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKET--RITTVAGTKPYMAPEMFSSRKESG 199

  Fly   444 HDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQK--EQPMI--PSSFSANARDFVLK 504
            :..||||||:||..:|||.|..|:     .::.|..|:.|..  |..::  ||::||.....:.|
  Rat   200 YSFAVDWWSLGVTAYELLRGRRPY-----HIRSSTSSKEIVNMFETAIVTYPSAWSAEMVSLLKK 259

  Fly   505 MLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPT---------------LTAE 554
            :||.||.:|.  :|  .::|:..|:.:.:||..:..||....:.||               :...
  Rat   260 LLEPNPDQRF--SH--LTDIQNFPYMSDMNWDAVLQKRLIPGFVPTKGRLNCDPTFELEEMILES 320

  Fly   555 DDVQNFSNEFTDQVPEDPECDAPPSRIRLFRGYTYVAPEHL------------EQMRRDNHCEIQ 607
            ..:.........:..|..:||:|         ...:..|||            |:::||
  Rat   321 KPLHKKKKRLAKKEKEMKKCDSP---------QMCLLQEHLDAVQKEFIIFNREKVKRD------ 370

  Fly   608 YFNTGLQNI 616
             ||....||
  Rat   371 -FNQRQANI 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_001261697.1	S_TKc	261..530	CDD:214567	98/273 (36%)
		STKc_MSK_N	266..533	CDD:270735	95/271 (35%)
		S_TK_X	532..591	CDD:214529	10/73 (14%)
		S_TKc	632..886	CDD:214567
		PKc_like	632..885	CDD:304357
Stk32a	NP_001178823.1	STKc_Yank1	22..281	CDD:270730	98/274 (36%)
Stk32a	NP_001178823.1	S_TKc	23..270	CDD:214567	95/260 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000