DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JIL-1 and R04A9.7

DIOPT Version :9

Sequence 1:	NP_001261697.1	Gene:	JIL-1 / 39241	FlyBaseID:	FBgn0020412	Length:	1207	Species:	Drosophila melanogaster
Sequence 2:	NP_001024829.2	Gene:	R04A9.7 / 3565956	WormBaseID:	WBGene00044281	Length:	402	Species:	Caenorhabditis elegans

Alignment Length:	376	Identity:	142/376 - (37%)
Similarity:	220/376 - (58%)	Gaps:	17/376 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 LDNEAHQRDLEAVTDLKYYVKLYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMK 293
            :||......:.....::.:.||:..:.|:..||:.::::|.|.||:||.|||.|..|.|.:||||
Worm    17 VDNCDQLEKMMKQVSMQKFEKLFYPDDVAPKDFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMK 81

  Fly   294 VLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHS 358
            |:.|..|....|...|.:.||.:||.| .:|||..||||||::.||||||:|.:||||:|.|...
Worm    82 VITKRKVTGTEKDLRHARDERKILETI-NSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERK 145

  Fly   359 ENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAH 423
            .::.|...|.|::|::||:|.||...|:|||:|.:|::|:..||:||:||||.|....:.| :..
Worm   146 SDWPEEYARFYLSEIILAIEHLHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGE-KTL 209

  Fly   424 SFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQP 488
            :||||.||||||:||  ..|||.|||.|::|:|.:::..|..||.   |:. .::..:.|.|.:.
Worm   210 TFCGTHEYMAPEMIR--KVGHDHAVDVWALGILMYDMFMGGPPFT---GET-PADKDKSILKGKV 268

  Fly   489 MIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTA 553
            .:|...||:.:|.:.::::::|..|:     ...:||||.||..|:|.:|.....:.|:||||..
Worm   269 RLPPKLSASGKDLIKRIIKRDPTLRI-----TIPDIKEHEFFEEIDWDKLMAHDFEPPFKPTLAN 328

  Fly   554 EDDVQNFSNEFTDQVPEDPECDA----PPSRIRLFRGYTYVAPEHLEQMRR 600
            .:||.:|...||...||:..|.|    ...|..||.|:.:......::.|:
Worm   329 LEDVSHFDESFTSIAPEESPCKAIVTENEERNYLFNGFNFNRTSKTKETRK 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_001261697.1	S_TKc	261..530	CDD:214567	112/268 (42%)
		STKc_MSK_N	266..533	CDD:270735	113/266 (42%)
		S_TK_X	532..591	CDD:214529	21/62 (34%)
		S_TKc	632..886	CDD:214567
		PKc_like	632..885	CDD:304357
R04A9.7	NP_001024829.2	S_TKc	49..305	CDD:214567	112/268 (42%)
R04A9.7	NP_001024829.2	PKc_like	52..368	CDD:304357	134/328 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1132245at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920