Protein Alignment JIL-1 and S6kII

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_523437.2
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Alignment Length: 925
• Identity: 278/925 - (30%)
• Similarity: 416/925 - (44%)
• Gaps: 147/925 - (15%)

  Fly     5 QKQNYEILSGTSTSRLKNHQHPRESESLAYEEPDQMVRNHLNGQLVANGNGKTRKNSNSETMTNG 69
            |:|..:.:|.||:|  .|.:....|..|..:...:|       |:.::|...........|.|.
  Fly    16 QQQQQQHVSSTSSS--NNAEQQCSSSGLGLQLRQRM-------QITSSGCSSLAVTPMEHTPTE- 70

  Fly    70 KKSKLNTEGSGSGSGKTLNYNNNNNN-----------NNSISATNGQYTNSSSKTTSASARDYTY 123
                 :.|..|..||.|.:.....::           .:::.|...|:..|.:....::.:..|:
  Fly    71 -----DDESGGGNSGVTSSVTTVTSSQRRQQLQQVQQQSALQAALEQHHISPTADLDSARKRPTH 130

  Fly   124 RETISPPTPPSPPTTNVADIVCISDAESEDGRDPEREYYDQDMEEDEPNGIEIDESSSSLSKAKS 188
            |....||           :::.:||:||:                   .|:|        :..:.
  Fly   131 RTLCPPP-----------ELMELSDSESQ-------------------GGVE--------TGGRR 157

  Fly   189 NNAAAAAAAAAAAAAAAASKASSSTTPSYAMPTSNSTPLDLDNEAHQRDLEAVTDLKYYVKLYSD 253
            ..|                             |..|.| ||::.....:.|...:||..:|...|
  Fly   158 EGA-----------------------------TGRSAP-DLEDTEPLYETENEFELKEVIKEGHD 192

  Fly   254 EAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLE 318
            :| ..:.|:::||||.|::|:||||||:...|||.|||||||.|.|:  |.|....:..||.:|.
  Fly   193 KA-DPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATL--KVKDRVRSTNERKILA 254

  Fly   319 AIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQL 383
            .: .:.|:|.||||||:..||||:|||..||:|||.|.....|.|..|:.|:||:.||:..||.|
  Fly   255 DV-GHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTL 318

  Fly   384 GIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAV 448
            ||||||:|.||||||..|||.|:||||||  ...:..:.:|||||:|||||||:..  .|||.|.
  Fly   319 GIIYRDLKPENILLDEHGHIALTDFGLSK--QPLDGSKTYSFCGTVEYMAPEIVNR--KGHDFAA 379

  Fly   449 DWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRR 513
            ||||.|||.:|:|||..||   .||.:| |...:|.:.:..:|.:.|..|:..:..:.::||:.|
  Fly   380 DWWSFGVLMYEMLTGNLPF---HGQTRQ-ETMNQILRSKLGMPENLSPEAQSLLRALFKRNPQNR 440

  Fly   514 LGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPED-PECDAP 577
            ||...:...:||.|.||..|:|..|..|:.:.|:.|.: :.||...|..|:|.:.|.| |.....
  Fly   441 LGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAV-SRDDAFYFDVEYTSKSPRDSPGGPIS 504

  Fly   578 PSRIRLFRGYTYVAPEHLE-QMRRDNHCEIQYFNT-GLQNIPCRP----------------DDLE 624
            .|...:|||:::|||..|| |....|.|....... .:..||..|                .:..
  Fly   505 ASAHEIFRGFSFVAPVLLEGQCAGSNMCSTSASPLHSIAPIPAAPVGAPRTLPGVLPGNFHAEYN 569

  Fly   625 LGTRTSNGAYGTCHFVVDSSTDLVFLAKIIPLSKFRPSEVDALISC------ALDTTNHKNIVSY 683
            |......|.:..|......::...:..|:|..:....:.......|      .|...||.|||:.
  Fly   570 LLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYGNHPNIVTL 634

  Fly   684 HGTFREKCETWIVMEYLSGPELTASI----RMDEDSCREIFLQLVMAVRHIHSKHFIHGDLKPEN 744
            :..:.:....::|||.|.|.||...|    :|.|.....:...:..||.::|....:|.||||.|
  Fly   635 YSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLHEHGVVHRDLKPSN 699

  Fly   745 IMFEN--REDRTVKLIDFGSACYNNRFKSWKDKPRYTLDYAPPEMLADANLVTYSPAVDIYGLGA 807
            :::.:  :...|:||.|.|.|............|.||.::..||:|....   |..|.||:.||.
  Fly   700 MIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQG---YDLACDIWSLGV 761

  Fly   808 TLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPA 872
            .||.||.|..|:....:|      :...:.||:..|..:..|.||...|...:.|:...|...|.
  Fly   762 LLYIMLSGRTPFASTPND------SPDVILKRIGSGQIDFTSSRWALISVPAKELLRQMLHIVPE 820

  Fly   873 DRPTLSDILDSEWLQ 887
            :|||.:.||:.:||:
  Fly   821 NRPTAARILEHDWLR 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	130/266 (49%)
		S_TK_X	532..591	CDD:214529	18/59 (31%)
		S_TKc	632..886	CDD:214567	70/265 (26%)
S6kII	NP_523437.2	STKc_RSK_N	203..517	CDD:270734	149/325 (46%)
		STKc_RSK_C	567..883	CDD:270993	73/278 (26%)