Protein Alignment JIL-1 and SNX15

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_037438.2
• Gene: SNX15 / 29907
• HGNCID: 14978
• Length: 342
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 55/250 - (22%)
• Similarity: 81/250 - (32%)
• Gaps: 81/250 - (32%)

  Fly   871 PADRPTLSDILDSEWLQYGSNDPDVDI----ILPQQMVVDL------SEDTMEQPTGGMFDDQQQ 925
            |.|.|.||.:|.:|  :.|..:.:|.:    ..|.|..:||      :|:....|..|...:.:.
Human   150 PPDDPRLSQLLPAE--RRGLEELEVPVDPPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAEL 212

  Fly   926 LEFMHDKSAEDEGITLVSEPMDTTVATHESRRNAAAFSSVVAPTTDDEIVHERFDPAFEVQADFY 990
            ..|  |..:::||                    ||...:.||.....|:...|.|
Human   213 ALF--DPFSKEEG--------------------AAPSPTHVAELATMEVESARLD---------- 245

  Fly   991 GFDENAPPLPLPEEYYSELPLPEEDRQYIPPPPALIPVEPETTFRRPRTRQQRRTESQLVQPVSV 1055
                ..|..|..:|       .|||.:..|.|..|.......|       |..|.|.......::
Human   246 ----QEPWEPGGQE-------EEEDGEGGPTPAYLSQATELIT-------QALRDEKAGAYAAAL 292

  Fly  1056 ATYEDSKASLRVLMQQLPPPGDNVVAR----------IPKRTHRVVR----TLPP 1096
            ..|.|   .:.||:|.:  |.|.:.||          ..||...::|    .|||
Human   293 QGYRD---GVHVLLQGV--PSDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735
		S_TK_X	532..591	CDD:214529
		S_TKc	632..886	CDD:214567	7/14 (50%)
SNX15	NP_037438.2	PX_domain	9..126	CDD:470617
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..267		8/42 (19%)
		MIT_SNX15	267..341	CDD:239140	17/85 (20%)