Protein Alignment JIL-1 and STK38L

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_055815.1
• Gene: STK38L / 23012
• HGNCID: 17848
• Length: 464
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 145/473 - (30%)
• Similarity: 226/473 - (47%)
• Gaps: 104/473 - (21%)

  Fly   206 ASKASSSTTPSYAMPTSNST-------PLDLDN------------EAHQRDLEAVTDLK------ 245
            |..|.::||    .|.||.|       .|.|:|            |..|:.||...:.:
Human     2 AMTAGTTTT----FPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEE 62

  Fly   246 -------------YYVKLYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNK 297
                         .:::| ....:.|:||:.::|:|.||:|.|.||:|   .|.|.:||||:|.|
Human    63 KKLRRSQHARKETEFLRL-KRTRLGLDDFESLKVIGRGAFGEVRLVQK---KDTGHIYAMKILRK 123

  Fly   298 ITVVQKRKTAEHTKTER-VVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENF 361
            ..:::|.:.| |.:.|| :::||  ...::|.:.|:||....|||:::|..||::.|.|...:..
Human   124 SDMLEKEQVA-HIRAERDILVEA--DGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTL 185

  Fly   362 EESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENE---YR-- 421
            .|...:.||:|.|||::.:||||.|:||||.:|:|||.:||:.||||||...|...:.   ||
Human   186 TEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNL 250

  Fly   422 -----------------------------AHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLT 457
                                         |:|..||.:|:|||:..  ..|::...||||:||:.
Human   251 THNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFM--QTGYNKLCDWWSLGVIM 313

  Fly   458 FELLTGASPFATSDGQVQQSEISRRIQ--KEQPMIPSS--FSANARDFVLKMLEKNPKRRLGGNH 518
            :|:|.|..||.:...|    |..|::.  ||..:.|..  .|..|:|.:|:.. .:.:.|:|.:
Human   314 YEMLIGYPPFCSETPQ----ETYRKVMNWKETLVFPPEVPISEKAKDLILRFC-IDSENRIGNS- 372

  Fly   519 RDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNF----SNEFTDQVPEDPECDAPPS 579
             ...|||.||||.|::|:.:|.:....|.:  :.:.||..||    .::....||...|.|. .|
Human   373 -GVEEIKGHPFFEGVDWEHIRERPAAIPIE--IKSIDDTSNFDDFPESDILQPVPNTTEPDY-KS 433

  Fly   580 RIRLFRGYTYVAPEHLEQ 597
            :..:|..|||...|.|.|
Human   434 KDWVFLNYTYKRFEGLTQ 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	106/305 (35%)
		S_TK_X	532..591	CDD:214529	17/62 (27%)
		S_TKc	632..886	CDD:214567
STK38L	NP_055815.1	MobB_NDR_LATS-like	12..86	CDD:459252	12/74 (16%)
		S100B binding. /evidence=ECO:0000250	63..88		1/25 (4%)
		STKc_NDR2	87..452	CDD:270776	129/383 (34%)