DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JIL-1 and Sgk1

DIOPT Version :9

Sequence 1:	NP_001261697.1	Gene:	JIL-1 / 39241	FlyBaseID:	FBgn0020412	Length:	1207	Species:	Drosophila melanogaster
Sequence 2:	NP_001155317.2	Gene:	Sgk1 / 20393	MGIID:	1340062	Length:	524	Species:	Mus musculus

Alignment Length:	345	Identity:	138/345 - (40%)
Similarity:	199/345 - (57%)	Gaps:	25/345 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 NDFKIIRVLGTGAYGRVFLVRKLTRHDAGKL-YAMKVLNKITVVQKRKTAEHTKTERVVLEAIQR 322
            :||..::|:|.|::|:|.    |.||.|.:: ||:|||.|..:: |:|..:|..:||.||....:
Mouse   189 SDFHFLKVIGKGSFGKVL----LARHKAEEVFYAVKVLQKKAIL-KKKEEKHIMSERNVLLKNVK 248

  Fly   323 NPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIY 387
            :||||.||::||::.|||.|||:.||||||.||.....|.|.|.|.|.||:..||..||.|.|:|
Mouse   249 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVY 313

  Fly   388 RDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWS 452
            ||:|.||||||.:|||||:||||.| ...|:.....:||||.||:|||::...|  :|..||||.
Mouse   314 RDLKPENILLDSQGHIVLTDFGLCK-ENIEHNGTTSTFCGTPEYLAPEVLHKQP--YDRTVDWWC 375

  Fly   453 VGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGN 517
            :|.:.:|:|.|..||.:.:.......|..:..:.:|.|.:|    ||..:..:|:|:..:|||..
Mouse   376 LGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNS----ARHLLEGLLQKDRTKRLGAK 436

  Fly   518 HRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPPSRI- 581
            . |..|||.|.||:.|||.:|..|:...|:.|.::...|:::|..|||:: |........|..|
Mouse   437 D-DFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEE-PVPSSIGRSPDSIL 499

  Fly   582 ---------RLFRGYTYVAP 592
                     ..|.|::|..|
Mouse   500 VTASVKEAAEAFLGFSYAPP 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_001261697.1	S_TKc	261..530	CDD:214567	116/269 (43%)
		STKc_MSK_N	266..533	CDD:270735	117/267 (44%)
		S_TK_X	532..591	CDD:214529	18/68 (26%)
		S_TKc	632..886	CDD:214567
		PKc_like	632..885	CDD:304357
Sgk1	NP_001155317.2	STKc_SGK1	183..521	CDD:270753	138/345 (40%)
Sgk1	NP_001155317.2	S_TKc	191..448	CDD:214567	116/269 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910