DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JIL-1 and sgk-1

DIOPT Version :9

Sequence 1:	NP_001261697.1	Gene:	JIL-1 / 39241	FlyBaseID:	FBgn0020412	Length:	1207	Species:	Drosophila melanogaster
Sequence 2:	NP_001041299.1	Gene:	sgk-1 / 181697	WormBaseID:	WBGene00004789	Length:	463	Species:	Caenorhabditis elegans

Alignment Length:	376	Identity:	144/376 - (38%)
Similarity:	212/376 - (56%)	Gaps:	28/376 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 LDNEAHQRD------LEAVTDLKYYVKLYSDE--AVSLNDFKIIRVLGTGAYGRVFLVRKLTRHD 285
            :||.....|      ||:..|.:..|.|...|  ..:.|||..:..:|.|::|||:.||   ..:
Worm    95 VDNNLRSEDVRRFFHLESPDDDENNVDLGPSERKTATANDFDYLTTIGKGSFGRVYQVR---HKE 156

  Fly   286 AGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGE 350
            ..|:||||:|:| ..::|:...:|...||.||....::|||||||::||:..|||.|||..||||
Worm   157 TKKIYAMKILSK-EHIRKKNEVKHVMAERNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGE 220

  Fly   351 LFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILT 415
            ||:||...::|.|||.|.|.||:..||..||:..|||||:|.||:|||.:|::||:||||.| ..
Worm   221 LFSHLQREKHFSESRSRFYAAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCK-ED 284

  Fly   416 AENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEIS 480
            .:......:||||.||:|||||...|  :|..||||.:|.:.:|::.|..||.:.|    .:|:.
Worm   285 MQGSKTTSTFCGTPEYLAPEIILKKP--YDKTVDWWCLGSVLYEMIFGLPPFYSKD----HNEMY 343

  Fly   481 RRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHR-DASEIKEHPFFNGINWQELRTKRRK 544
            .:|..:...:..:.|....:.:..:|:|:..:|||  || |..:|::||||..::|.:|..:..|
Worm   344 DKIINQPLRLKHNISVPCSELITGLLQKDRSKRLG--HRNDFRDIRDHPFFLPVDWDKLLNRELK 406

  Fly   545 APYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPPS-----RIRLFRGYTYV 590
            ||:.|.:....|..|.|.||. ::..||...||..     |...|..:|:|
Worm   407 APFIPKVKNAMDTSNISKEFV-EIQIDPSSLAPQQLAVTHRDHDFENFTFV 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_001261697.1	S_TKc	261..530	CDD:214567	112/269 (42%)
		STKc_MSK_N	266..533	CDD:270735	113/267 (42%)
		S_TK_X	532..591	CDD:214529	19/64 (30%)
		S_TKc	632..886	CDD:214567
		PKc_like	632..885	CDD:304357
sgk-1	NP_001041299.1	S_TKc	135..392	CDD:214567	112/269 (42%)
sgk-1	NP_001041299.1	STKc_SGK	139..456	CDD:270727	131/330 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910