Protein Alignment JIL-1 and pdk-1

DIOPT Version :10

• Sequence 1: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_001024743.1
• Gene: pdk-1 / 180475
• WormBaseID: WBGene00003965
• Length: 636
• Species: Caenorhabditis elegans
• Alignment Length: 793
• Identity: 161/793 - (20%)
• Similarity: 280/793 - (35%)
• Gaps: 269/793 - (33%)

  Fly   175 EIDESSSSLSKAKSNNAAAAAAAAAAAAAAAASKASSSTTPSYAMPTS-NSTPLDLDNEAHQRDL 238
            ::..:::||....:||                    .:|:...|.||: |.||...::|   ..|
 Worm     3 DLTPTNTSLDTTTTNN--------------------DTTSDREAAPTTLNLTPTASESE---NSL 44

  Fly   239 EAVTDLKYYVKLYSDEAV--SLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVV 301
            ..||......|...:...  :.|||..::.:|.|||.:||..|::.. ||  ::|:|||
 Worm    45 SPVTAEDLIAKSIKEGCPKRTSNDFMFLQSMGEGAYSQVFRCREVAT-DA--MFAVKVL------ 100

  Fly   302 QKRKTAEHTKTERVVLEAIQRN------------PFLVSLHYAFQSSSKLYLVLDFANGGELFTH 354
            ||.....|.|.:.::.|   :|            ||:..|:..|...:::|.|:.....|:|...
 Worm   101 QKSYLNRHQKMDAIIRE---KNILTYLSQECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGES 162

  Fly   355 LYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKI------ 413
            |.|..:|:....:.:.:|::..|:.||...|::||:|.:|:|:..:|||:::|||.::.
 Worm   163 LCHFGSFDMLTSKFFASEILTGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQL 227

  Fly   414 -------------------------------LTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSA 447
                                           :..||..|..:|.||..|::||::..|..|..:
 Worm   228 SQEGFTDANQASSRSSDSGSPPPTRFYSDEEVPEENTARRTTFVGTALYVSPEMLADGDVGPQT- 291

  Fly   448 VDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKR 512
             |.|.:|.:.|:.|.|..||..    |.|..:.:|||:.....|..|...|.:.:.|:|.::|..
 Worm   292 -DIWGLGCILFQCLAGQPPFRA----VNQYHLLKRIQELDFSFPEGFPEEASEIIAKILVRDPST 351

  Fly   513 RLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAP 577
            |:     .:.|:..|.||..::|..:      |..||.:
 Worm   352 RI-----TSQELMAHKFFENVDWVNI------ANIKPPV-------------------------- 379

  Fly   578 PSRIRLFRGYTYVAPEHLEQMRRDNHCEIQYFNTGLQNIPCRP--DD------LELGT------- 627
               :..:...|:..||:             |.|.|    |..|  ||      :.||.
 Worm   380 ---LHAYIPATFGEPEY-------------YSNIG----PVEPGLDDRALFRLMNLGNDASASQP 424

  Fly   628 ---RTSNGAYGTCHFVVDSSTDLVFLAKIIPLSKFRPSEVDALISCALDTTNHKNIVSYH----- 684
               |.||         |:...| .|:::|.|.:.....:..|..:..|:....||  .:|
 Worm   425 STFRPSN---------VEHRGD-PFVSEIAPRANSEAEKNRAARAQKLEEQRVKN--PFHIFTNN 477

  Fly   685 -------------GTFREKCETWIVME-----YLSGPELTASIRMDEDSCREIFLQLVMAVRHIH 731
                         |.|..: ..:::.|     |:..|.|.....:....|.::.|:       ..
 Worm   478 SLILKQGYLEKKRGLFARR-RMFLLTEGPHLLYIDVPNLVLKGEVPWTPCMQVELK-------NS 534

  Fly   732 SKHFIHGDLKPENIMF----ENREDRTVKLID-------------FGSACYNNRFKSWKDKPRYT 779
            ...|||   .|..:.:    |.:.|...|.|:             |.||..:..|.|
 Worm   535 GTFFIH---TPNRVYYLFDLEKKADEWCKAINDVRKRYSVTIEKTFNSAMRDGTFGS-------- 588

  Fly   780 LDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGT 844
                                  |||...:...|:...:..|:.::..:..|....::.|::
 Worm   589 ----------------------IYGKKKSRKEMMREQKALRRKQEKEEKKALKAEQVSKKL---- 627

  Fly   845 FNQRSMRWESASP 857
                ||:.:..||
 Worm   628 ----SMQMDKKSP 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	81/315 (26%)
		S_TK_X	532..591	CDD:214529	5/58 (9%)
		S_TKc	632..886	CDD:214567	42/266 (16%)
pdk-1	NP_001024743.1	STKc_PDK1	67..364	CDD:270733	82/319 (26%)
		PH_PDK1	464..570	CDD:241293	19/118 (16%)