Protein Alignment Noc1 and Cebpz

DIOPT Version :10

• Sequence 1: NP_648431.3
• Gene: Noc1 / 39240
• FlyBaseID: FBgn0036124
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: NP_001019977.1
• Gene: Cebpz / 12607
• MGIID: 109386
• Length: 1052
• Species: Mus musculus
• Alignment Length: 1170
• Identity: 322/1170 - (27%)
• Similarity: 526/1170 - (44%)
• Gaps: 238/1170 - (20%)

  Fly   108 KPQKIKFGEDREAVHQKPFNKNNH------KHNGQKSDFANKPQKIKFTDDGEDEVTANSSNT-- 164
            :|:::....|.|........||..      :..|.|.|:.    .:...|:.|:.|......|
Mouse    17 RPKQVTEDPDEEDEEDGDEGKNGFSLEEVLRLGGTKQDYL----MLATLDENEEVVDGGKKGTID 77

  Fly   165 ------------KTEPTKKSQKIKFGDDGESKENFKKPQRIKFDEDGAGKNVSDSDGDSDEELGD 217
                        .....|.|:.:...|:.|.|||..|.:......:...:..::....|::::.:
Mouse    78 DLQQGELESFIQNLNLAKYSKSLIEEDEPEKKENTSKKEAKLLKVENKKQKATEGKKTSEKKVKN 142

  Fly   218 S-----------ISKKHNKYQSKIDEDEESQK-------KWYHVHPDYPSTDEVLDMKENDQLEL 264
            .           :||.....|..:.|..|.|.       |||.:  :| |.:..|:::..|.:..
Mouse   143 KTVPEQRPESCPVSKAKKDKQPDVFEFLERQTMLLRPGGKWYDM--EY-SGEYSLELQPPDVVSK 204

  Fly   265 YN-LCKNSFEAEKITF----NKRNPSDARWLQTALHKGTAKDRANAGALLVTSNPLGNLEALSTL 324
            |. |.:..:|.|...|    |.:....:.|::..:..||..||..|..||:..:.:..|:.:.||
Mouse   205 YKALAQKLYEHEVSLFKSKTNNQKGGSSTWMKAIVSSGTLADRMAAMILLIQDDAVHTLQFVETL 269

  Fly   325 IGFCKISNKASNDVIAVLTDLWQEV----LLPPNRKL--LAVHTRGADWKKLKKDENLRNEQKRR 383
            :...|  .|.|.....:..|.::|:    |||.:|||  .:.|    .:.||::..:...:.:.|
Mouse   270 MSLVK--KKGSKQQCLMALDTFKELLITDLLPDSRKLRVFSQH----PFHKLEELSSGNKDSRDR 328

  Fly   384 IYAYWHFESELKDQYHEFLKNVMQGLQTGQEHN-----KNSSIVSAARLLAYAPEKEQLLLTMLV 443
            ....|::|.:||....||    :|.|:| ..|:     |..::|:|..||...||:|:.||..::
Mouse   329 RLILWYYEHQLKHLVAEF----VQVLET-LSHDSLVTTKTRALVAAHELLCDKPEEEKALLVQVI 388

  Fly   444 NKLGDPIAKIASKALHHLSEVAQKHPNMCGVIVAEAEKLLFRNNISERAQHFALCFLSSIAPS-G 507
            ||||||..:||:||.|.|..:.:|||||.||:.||.|:||||:|||.:||::|:|||:.:..| .
Mouse   389 NKLGDPQNRIATKASHLLEVLLRKHPNMKGVVCAEIERLLFRSNISPKAQYYAICFLNQMVLSHE 453

  Fly   508 RPEVCTKLVNICFALFKVLVQKGAVNNRTMQAILRCLQKAIVEAKPAKDSNGELLTKEMQDTIYR 572
            ..|:..||:.:.|..|:..::|..:.::.:.|||..:.:|...::...|.     .:|..||:::
Mouse   454 ESELANKLITLYFCFFRTCIKKKDIESKMLSAILTGVNRAYPYSQIGDDK-----VREQVDTLFK 513

  Fly   573 LVHLADIRVAVQTLGLLLQLVAVKTEKSDRFYNALYVKLLDLNLINVGSKTAAHLLHIVHRAIHI 637
            ::|:.:...:||.|.||.|::..:...|||:|.|||.|:||..|.....:  |..|:::::::..
Mouse   514 VLHVVNFNTSVQALMLLFQVMNSQQTISDRYYTALYRKMLDPGLTTCSKQ--AMFLNLIYKSLKA 576

  Fly   638 DNHVARAQAFVKRLLQLTLYAPPHIAAGCLIVIHKLLRMRRELIGGTGASEEVEEGSKVVLPISA 702
            |..:.|.:||||||||:|....|....|.|.::.::|:.:.:|                    .:
Mouse   577 DIMLRRVKAFVKRLLQVTCTQMPPFICGALYLVSEILKAKPDL--------------------RS 621

  Fly   703 DLDKFGSDDEEVYEDVKDEADDTKDSNPLEEKADNDVKS-----------------SASSWHHAR 750
            .||.....|||.:.||.|::||.|.::..:|.|.:.||.                 .|:||.|
Mouse   622 QLDDHPESDEENFVDVGDDSDDEKFTDADKETATDAVKEVESKETEPESSAEAEKPKAASWVH-- 684

  Fly   751 VAATEAKVRDIDSCK-------YDPYHRVPAFAGAAYALRHELLLLRQHYHPTVQVFAEQILQQS 808
                      .|:.|       |||:.|.|.|.||......||..|.:|:||:|.:||:.||:.:
Mouse   685 ----------FDNLKGGKQIKTYDPFSRNPLFCGAENTTLWELKKLSEHFHPSVALFAKTILEGN 739

  Fly   809 RIDYYGDPLRDFGLPHFLERFAFKNPKKLEASQAAENATVAHKR-YMAHGARGRPVKS---LTK- 868
            .|.|.||||:||.|..||:||.::|||..:..:..::..:..|| :.....|...|.|   |.|
Mouse   740 CIQYSGDPLQDFTLMRFLDRFVYRNPKLHKGKENTDSVVMQPKRKHFMKNVRDLAVNSKEFLAKE 804

  Fly   869 -ANCTEDEMFIFNFLEHKRRQAEIVAQNKKQKEIKKDAAEEGDDGEAGEEYLKEGEVDDDEFEAY 932
             :....||:|.:.:.              |:..:.||..:...|.|:.|      ::||:|||..
Mouse   805 ESQIPVDEVFFYRYY--------------KKVAVVKDKQKRSADEESIE------DIDDEEFENM 849

  Fly   933 LDGYFGKKFKEGVDEEQD------EEELNFLQELGGEIKKDKSKDKKKKKQSDKAEDEMDDIDDD 991
            :|.:           |.|      :::::|...:             ||.:..||:.|    |.:
Mouse   850 IDTF-----------EDDNCFPPGKDDIDFASNM-------------KKAKGAKADLE----DSE 886

  Fly   992 WGDDDLAEDEDDEIEGEDQSDDETGSIDLQPLDDDDDDDDDDDDEGSISEGGPGDSDSSDAPESP 1056
            ..|.:|.:.:|||:        ..||:       :|:|.:.|:|.|:..:  ..|.:|.||||.
Mouse   887 SSDGELGDLDDDEV--------SLGSM-------NDEDFEIDEDGGTFMD--VSDDESEDAPEF- 933

  Fly  1057 DEEDDDDEDAPP-----RSKKSRKDSTDMVGGRSFAKTLKQSHDMSSLFAAADDFSSLLEETAKV 1116
                   .||.|     :||:..:|..|..|.....|..|:|.:.||||.:|::|..||:|....
Mouse   934 -------ADANPKANTKKSKRKSEDDFDFAGSFQGQKKKKKSFNDSSLFVSAEEFGHLLDENMGS 991

  Fly  1117 KGQGTS-NAVFNKDKSSDKQLKWE-------ENRRSNSKSYKGKKFAGKPAAKGGRPQKAGKKRK 1173
            |..... ||:.|:|.:|.||||||       .||...|...|.|.|..|..|    |||..::||
Mouse   992 KFDTIGMNAMANRDNASFKQLKWEAERDDWLHNRDVKSIIKKKKNFRKKMKA----PQKPKRQRK 1052

  Fly  1174  1173
            Mouse  1053  1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Noc1	NP_648431.3	COG5593	211..955	CDD:227880	232/814 (29%)
Cebpz	NP_001019977.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40		5/22 (23%)
		PRK04195	<78..169	CDD:235250	12/90 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	122..158		2/35 (6%)
		COG5593	179..987	CDD:227880	269/933 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	621..677		15/55 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	876..969		32/121 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1032..1052		8/23 (35%)